Antibody Drug Conjugates: A frontier in cancer treatment
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Antibody Drug Conjugates: A frontier in cancer treatment
1–10 of 47 posts
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#2Every little step in fields like this is so encouraging. We keep getting better, but the cancers don't.
Ever more effective cocktails of drugs that target the cancers while minimising harm to everywhere else, the closer we get to attacking cancer cells from so many different directions they simply can't adapt in time and we wipe it out immediately (a cure). One can only hope.
I whether we might see even more investment into research like this as it gets closer to deliver curative, rather than just suppressive outcomes, as well
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#3Every little step in fields like this is so encouraging. We keep getting better, but the cancers don't. Ever more effective cocktails of drugs that target the cancers while minimising harm to everywhere else, the closer we get to attacking cancer cells from so many different directions they simply can't adapt in time and we wipe it out immediately (a cure). One can only hope. I whether we might see even more investme…
CAR-T may have a ~50% cure rate for blood cancers:
https://ashpublications.org/blood/article/141/19/2307/494672...
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#4Every little step in fields like this is so encouraging. We keep getting better, but the cancers don't. Ever more effective cocktails of drugs that target the cancers while minimising harm to everywhere else, the closer we get to attacking cancer cells from so many different directions they simply can't adapt in time and we wipe it out immediately (a cure). One can only hope. I whether we might see even more investme…
> whether we might see even more investment into research
The field would benefit greatly from even a fraction of the investment in the AI and crypto bubbles
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#5Pfizer acquired Seagen for $43 billion. Seagen has some very promising ADC’s in the queue.
https://www.pfizer.com/news/press-release/press-release-deta...
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#6Every little step in fields like this is so encouraging. We keep getting better, but the cancers don't. Ever more effective cocktails of drugs that target the cancers while minimising harm to everywhere else, the closer we get to attacking cancer cells from so many different directions they simply can't adapt in time and we wipe it out immediately (a cure). One can only hope. I whether we might see even more investme…
> whether we might see even more investment into research The field would benefit greatly from even a fraction of the investment in the AI and crypto bubbles
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Re: Antibody Drug Conjugates: A frontier in cancer treatment
#7> The Food and Drug Administration approves new cancer treatments when they are shown in clinical trials to be more effective than the current approved cancer treatment for a given cancer type. The approval comes when the treatment extends lifespan without overly increasing the risks of serious side effects.
This standard just doesn’t make sense to me. Every case is different, so why “throw out” a treatment option for only being within the margin of error of efficacy on a general population? It must be incredibly frustrating for patients to know about these treatments…
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#8> The Food and Drug Administration approves new cancer treatments when they are shown in clinical trials to be more effective than the current approved cancer treatment for a given cancer type. The approval comes when the treatment extends lifespan without overly increasing the risks of serious side effects. This standard just doesn’t make sense to me. Every case is different, so why “throw out” a treatment option fo…
It's fine to ask for an approval for a part of the population (e.g. people with cancer exhibiting particular markers).
Re: Antibody Drug Conjugates: A frontier in cancer treatment
#9Re: Antibody Drug Conjugates: A frontier in cancer treatment
#10Pfizer acquired Seagen for $43 billion. Seagen has some very promising ADC’s in the queue. https://www.pfizer.com/news/press-release/press-release-deta...
It's weird to think of a hopeful story of a $43Bn acquisition.