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Impact of early life adversity on reward processing in young adults (2014)

journals.plos.org

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Re: Impact of early life adversity on reward processing in young adults (2014)

#2
So, is this just a way to do early measurements, to determine if someone might develop ADHD later.

Not any indicator of things to 'do' to help not develop ADHD later? No actions to take?

" In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventral striatum during reward anticipation and higher activation in the right insula during reward delivery."

Re: Impact of early life adversity on reward processing in young adults (2014)

#3

So, is this just a way to do early measurements, to determine if someone might develop ADHD later. Not any indicator of things to 'do' to help not develop ADHD later? No actions to take? " In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventr…

It says towards the end of the abstract that righting this balance, increasing anticipation dopamine and lowering reward receiving dopamine, could help with adhd

Re: Impact of early life adversity on reward processing in young adults (2014)

#4

So, is this just a way to do early measurements, to determine if someone might develop ADHD later. Not any indicator of things to 'do' to help not develop ADHD later? No actions to take? " In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventr…

>Not any indicator of things to 'do' to help not develop ADHD later? No actions to take?

Reduce early life adversity.

Re: Impact of early life adversity on reward processing in young adults (2014)

#6

So, is this just a way to do early measurements, to determine if someone might develop ADHD later. Not any indicator of things to 'do' to help not develop ADHD later? No actions to take? " In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventr…

> No actions to take?

The actions to take would appear to depend upon whether one wishes to have fewer adults with lifetime ADHD symptoms, or more*.

The childhood adversities to affect either way are from [RutterQuinton77] and listed in TFA's Table S1, abbreviated here:

  *Low educational level  parent with neither school nor training
  *Overcrowding           more than 1.0 person/room or housing
The ones marked with * are those factors I believe relatively easier to address via social policy.

EDIT: TFA uses different measures, discussed in the section "Definition of Rutter’s indicators of adversity (RIA)":

  low social class     both parents
  marital discord      parents not at same address
  large family size    4+ children
  paternal criminality
  maternal disorder    ICD-8: 290–315 or ICD-10: F00-F99
  foster placement
* for instance, [Huxley32] mentions the practice of inducing fetal alcohol syndrome in order to ensure a steady supply of menial labour

Re: Impact of early life adversity on reward processing in young adults (2014)

#7

So, is this just a way to do early measurements, to determine if someone might develop ADHD later. Not any indicator of things to 'do' to help not develop ADHD later? No actions to take? " In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventr…

> No actions to take? The actions to take would appear to depend upon whether one wishes to have fewer adults with lifetime ADHD symptoms, or more*. The childhood adversities to affect either way are from [RutterQuinton77] and listed in TFA's Table S1, abbreviated here: *Low educational level parent with neither school nor training *Overcrowding more than 1.0 person/room or housing The ones marked with * are those fa…

More than 1 person per room??? Surely everyone having their own room is a very recent development?

Re: Impact of early life adversity on reward processing in young adults (2014)

#8

"Moreover, a similar activation pattern related to lifetime ADHD may suggest that the impact of early life stress on ADHD may possibly be mediated by a dysfunctional reward pathway." What is a dysfunctional reward pathway?

It is stated just above the quoted text.

Basically a lower-than-expected response to reward anticipation and a higher-than-expected response upon reward delivery.

I.e. the typical ADHD problem of instant vs delayed gratification and how the brain responds to it.

Neurotypical people’s brains seem to be better at rewarding in anticipation and not just on actual delivery.

IIUC

Re: Impact of early life adversity on reward processing in young adults (2014)

#9

Earlier quoted context omitted.

> No actions to take? The actions to take would appear to depend upon whether one wishes to have fewer adults with lifetime ADHD symptoms, or more*. The childhood adversities to affect either way are from [RutterQuinton77] and listed in TFA's Table S1, abbreviated here: *Low educational level parent with neither school nor training *Overcrowding more than 1.0 person/room or housing The ones marked with * are those fa…

More than 1 person per room??? Surely everyone having their own room is a very recent development?

I think that's the whole house, not just bedrooms.

Re: Impact of early life adversity on reward processing in young adults (2014)

#10

"Moreover, a similar activation pattern related to lifetime ADHD may suggest that the impact of early life stress on ADHD may possibly be mediated by a dysfunctional reward pathway." What is a dysfunctional reward pathway?

The brain releases dopamine as a "reward"; it's a feel-good chemical that contributes to positive reinforcement of various behaviors. People with ADHD have limited dopamine response, which can express as a lack of motivation relative to others.
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