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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#871

Post by jvanderbot »

pizza wrote: post #787
unlikelytomato wrote: post #746

Earlier quoted context omitted.

I would say my concerns are far more in the range of downstream effects from the medication. Specifically, I am concerned with muscle retention. Concerns aside, it's a little hard of an argument to swallow having visited many other countries where these things are simply not an issue. How can it be argued that the cause is anything other than behavior when so many others are doing just fine? There is more to this sto…

It seems the article is now behind a paywall (can only get a reddit link w/ a screenshot atm [0]) but there was a study that showed body composition after 25% weight loss in terms of fat mass and fat-free mass (and the portion of fat-free mass that was skeletal muscle mass) after traditional several interventions, and also compared the breakdown of weight lost in terms of FM and FFM for several GLP-1 medications: - d…

How will the person have less insulin resistance when GLP-1 medications stimulate the release of insulin?

It seems to me we're curbing eating by flooding with insulin, when one of the big damaging effects of overeating is insulin floods. (Or perhaps I'm misreading, perhaps insulin floods are only bad b/c they cause insulin resistance which causes more overeating?)

Re: How long til we're all on Ozempic?

#872

Post by cthalupa »

wiseowise wrote: post #830
OptionOfT wrote: post #420

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

> Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse? For the same reason why skinny person taking steroids is frowned upon - it is perceived as a shortcut.

Supra-physiological levels of testosterone and steroids have incredibly well known and well researched short, medium, and long term side effects. They've been well known for forever.

In an alternate world where steroids had a good safety profile, it would be ridiculous to not use them if you were looking to add on muscle mass.

Re: How long til we're all on Ozempic?

#873

Post by j-a-a-p »

autoexec wrote: post #569
j-a-a-p wrote: post #520

Earlier quoted context omitted.

The willpower frame actually works pretty well for a lot of people. If not than in our society almost everybody would be obese. This pill will make things worse for the group that hangs out in the treadmills and drinks green and disgusting smoothies. On topic, very happy this medicine exists, but let's pray god will keep the prescription only for BMI > 35.

> The willpower frame actually works pretty well for a lot of people. If not than in our society almost everybody would be obese. In the US nearly 75% of the population is overweight and almost half are clinically obese. Sounds like "willpower" isn't working for the vast majority of people.

That is not logical. If willpower fails, how could a pill be a solution? That is like suggesting to give everybody methadon, because the substance dependency issues are just too overwhelming. Or even better, give certain kids from 12 to 6 years old a gun to solve the school shootings issue.

If we give up on willpower, we have no plan b.

Re: How long til we're all on Ozempic?

#874

Post by grecy »

adrian_b wrote: post #566
arcticbull wrote: post #105

Earlier quoted context omitted.

> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…

I hear very often this theory that "it just doesn't work". To be fair, I had also believed this for many years. However, all the people who claim that "it just doesn't work", have never made any serious attempt to do "it", so they cannot know whether it does work or not. I have been obese for more than a decade, during which I have made several attempts to lose weight, which have all failed, because they were not don…

I’m sorry for the downvotes.

What you did takes a lot of discipline and hard work, and you did it.

Of course eating less calories than you consume results in weight loss, and you stuck with it. Congrats and Thanks for the details

Re: How long til we're all on Ozempic?

#875

Post by grecy »

andrewla wrote: post #239

I think Ozempic is a treatment of a symptom but not the underlying condition, but unlike many of the posters here, I do not think the underlying condition is "obesity". The below is mostly speculation. Research especially into people with healthy body weight seems to indicate that there is something going on that is causing widespread obesity. That is, there's some sort of environmental "GLP-1 Turbocharger". Maybe it…

You are doing an awful lot of mental gymnastics in search of a boogeyman that does not exist.

How mammals ingest, process, store and burn energy has been well understood for a very long time.

You know why some domestic dogs and cats are overweight? Is it ADHD or microplastics? Of course not, it’s because they’ve been eating more energy thaN they have been burning for a while.

Ozempic only stops you wanting to eat more, which perfectly proves the point. The boogeyman you are searching for is eating more energy than you burn.

Re: How long til we're all on Ozempic?

#876

Post by snvzz »

valunord wrote: post #146

Fuck that. Just have some willpower! Some of us have been doing OMAD without assistance, just grunting through the stress and pain for years. It's much healthier than drugging up.

After one year of OMAD and 15kg less, I am now at about ideal weight by BMI (22).

I didn't even need much if any willpower past the first couple days.

This push for Ozempic is utter madness.

Re: How long til we're all on Ozempic?

#877

Post by snvzz »

Waterluvian wrote: post #708

I’ve lost 40lbs this year since I started trying. All I did was cut out breakfast and only ever eat if I feel hungry. Thr first few weeks were hard. My body was hungry all the time. Now I feel hungry far less. I don’t get hungry until noon. The problem is that if I ever cheat and pig out, like, say, this Thanksgiving weekend, it resets and I feel a week or two of miserable hunger again. If I could cheat my brain in a…

>If I could cheat my brain in any way, it would be just not feeling hungry until noon, regardless of past actions.

Not eating too close to going to sleep suffices. I'd set the minimum at a good 4h.

Re: How long til we're all on Ozempic?

#879

Post by snvzz »

pfdietz wrote: post #174
Eumenes wrote: post #139

The day Ozempic/similar drugs become approved for weight loss under ACA/Medicare is the day I stop paying taxes.

Good news! You'll probably be able to get GLP-1 agonists in prison.

There are legal ways to stop paying taxes in a country, such as moving elsewhere.

It is a much safer assumption to make than tax evasion.

Re: How long til we're all on Ozempic?

#880

Post by arandomusername »

makeitdouble wrote: post #779
itsoktocry wrote: post #760

Earlier quoted context omitted.

For me, personally, it's that we don't really know the long term effects of these drugs ie are you actually "healthier". But we do know that diet and exercise work.

> we do know that diet and exercise work. Stricly speaking we don't. This is "common sense" and the official recommendation, but fundamentally we don't have solid long term reproductible experiments[0], and due to the nature of the problem (humans living their life in a complex society) we'll probably never have a good answer. I've read many many studies spanning a few months and calling it a day (did the subjects re…

> Stricly speaking we don't.

Yes we do, because it works. Exercise burns more calories. Diet limits your calorie intake.

If you rebound into not doing exercise and overeating, that's on you.

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