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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#531

Post by taejavu »

OptionOfT wrote: post #420

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

What kind of food do you and your wife cook? How much meat? How much gluten? Real butter or canola oil infused “spreads”? What oil do you cook with? Vegetable? Sunflower?

If you’re eating the right thing for your body, you’ll be satiated when you eat your full.

Re: How long til we're all on Ozempic?

#532

Post by ajkjk »

dfxm12 wrote: post #170

Instead of a system that makes these drug available for purchase, I'd rather live in a system that promotes healthy food and active behavior. Unfortunately, I have to drive everywhere, work too many hours to have free time for recreation and have no idea which government subsidy is going to help big ag likely at the expense of my health. All things being equal, I'd prefer to spend less money on prescriptions and have…

As compelling as the theory that "unhealthy behavior" is root cause of the obesity epidemics, at this point it seems to me that the weight of evidence suggests an actual physical disruption. It's not supposed to be _this hard_ for (some) people to maintain their weight; something is actually not working right.

https://slatestarcodex.com/2017/04/25/book-review-the-hungry... might be interesting in the same direction.

Re: How long til we're all on Ozempic?

#533

Post by rootusrootus »

apwell23 wrote: post #429
robohydrate wrote: post #299

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

Have you noticed any effect on gastric emptying. As someone with 'tummy issues' ( ibs/gerd ect) i am apprehensive of messing with my digestive systems.

Not the person you were responding to, but yes. Stomach empties much slower, which seems to effectively make it smaller. A normal size (pre-drug) meal will make me uncomfortably full and probably cause reflux.

That said, I've noticed in the past, and also now on this drug, that my gastrointestinal issues abate noticeably when I consume less food. Thought I had IBS and then I went on a significant diet and lost 40 pounds in 2020. The IBS resolved, and not after I lost 40 pounds -- it basically stopped altogether a matter of weeks after I changed my diet. That was educational. YMMV.

I'm still working out my approach to eating while taking tirzepatide. Old habits die hard, and I'm having to cut my meal size way back. This sucks because my problem with eating too much was about eating too often, or not when hungry, not about binging. So I have to eat pretty small meals now. It will take some adjustment to find the right way to get sufficient nutrition while volume limited, but I think it can be done.

Re: How long til we're all on Ozempic?

#536

Post by lurking15 »

op00to wrote: post #470
sumtechguy wrote: post #405

Earlier quoted context omitted.

I know someone who has lost about 60lbs. The reaction of most people is 'what pill did you take'. They find out it is basically no sugar and limited amounts of food with some mild exercise. Pretty much every one of them is 'thats hard' and do not do it. And frankly it is hard. Like 95% of a grocery store has way to much of what you need for your daily intake in some form or another. It is that 5% you have to dig thru…

GLP-1 agonists have already been marketed for 20 years. If there were effects, we'd have seen them by now.

Sharon Osbourne almost died, and I've read about enough people having serious problems on them including gastroparesis and bowel obstruction.

Re: How long til we're all on Ozempic?

#537

Post by spondylosaurus »

tjohns wrote: post #399
beezlebroxxxxxx wrote: post #336

Earlier quoted context omitted.

Is the official recommendation that you continue to take it for the rest of your life? Or, is there a schedule to "wean" people off of it?

Studies have show most people rapidly regain the weight once they stop taking GLP-1 drugs. The dysfunctional biochemical processes that contributed to overeating are still present if you discontinue the drug. Your body has a natural set-point for the weight it wants to be at, and the hunger and food noise comes right back as your body tries to get you back to your old weight. It's possible that after after a long eno…

"You'll regress if you stop taking the drugs" may be true, but it seems like a double standard to frame it as a knock against weight loss drugs when this also describes countless other interventions for chronic issues...

Your lupus will flare up again if you stop taking Plaquenil! Your eyesight will be bad again when you take off your glasses!

Re: How long til we're all on Ozempic?

#538

Post by slibhb »

mlsu wrote: post #381
robohydrate wrote: post #299

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

My view about obesity has shifted dramatically since Ozempic came out. Before this, I didn't think about it too much (I am not obese myself). I notice now that there is a LOT of judgement, bias(?), around obesity, that people, obese or not, carry with them [1]. I certainly carried that bias, and the reason I noticed it was because Ozempic is literally an external substance that you take that simply makes obesity go a…

> I notice now that there is a LOT of judgement, bias(?), around obesity, that people, obese or not, carry with them [1]. I certainly carried that bias, and the reason I noticed it was because Ozempic is literally an external substance that you take that simply makes obesity go away. So if you believe (like most of us unconsciously do) that obesity is a personal failing or an issue of willpower, an issue of personal merit -- HOW is it possible that a chemical pill, an external chemical process, can SO effectively resolve it? When no amount of hectoring and moralizing and willpower can? My inability to square that circle really changed my thinking about obesity in a fundamental way.

I see no contradiction here. That ozempic works doesn't imply that willpower isn't real or that people can't lose weight via diet and exercise.

> My view: It is a health condition, that people do not choose. Not unlike diabetes, celiac, or clinical depression. We should be focused on how to improve the lives of people who suffer with that health condition. We all agree insulin is unequivocally a good thing; that it's not a "personal failure" or "cheating" to take insulin; that it really is simple as, diabetes is a health condition and insulin is used to treat it. Ozempic? Same. Exact. Thing.

I'm very suspicious of "it's a health condition" applied to obesity, type 2 diabetes, and even depression. I absolutely believe that some people will be able to avoid or cure those "conditions" by changing their behavior. Of course that doesn't imply that there should be a taboo against medication to help people who can't. But my concern is that "it's a health condition" discourages people from examining their choices and making good ones.

Re: How long til we're all on Ozempic?

#539

Post by esfandia »

sph wrote: post #286
Uehreka wrote: post #271

Earlier quoted context omitted.

I gained about 50 pounds the past decade and the past year I’ve been trying to lose it. I weighed myself at the beginning: 205 lbs I started running 30 minutes per day (heartrate training targeting about 140-150), every day, for 10 months. I kept my diet the same as before (though with a protein bar after the run). Weighed myself every week or two, always within a couple pounds of 205. In March I ramped up my runs to…

What do you eat? I bet $10 either it's calorie-counted standard high carb diet or something that is low in protein and fats. The physiology of dieting, and avoiding hunger, is pretty well understood at this point. Just don't ask your GP or they'll just tell you to stop eating red meat and eat more cereals as the "solution".

Not the OP but I have tried to reduce my sugar intake, I'm walking more than before, and I still basically gain half a pound every year. I'd lose some weight for a few days, and gain it all back on the one day I'm a bad boy. It seems like there's an internal dial that decides what my weight is supposed to be, no matter how much I fight it. And the dial adds half a pound every year. I guess the dial is my metabolism as I age.

Re: How long til we're all on Ozempic?

#540

Post by bobro »

Retr0id wrote: post #528

As far as I can tell, the intended meaning of the question in the title is "how long until everyone who wants Ozempic can have it?". But at first I read it in a more cynical and sinister way, the more literal interpretation - how long until everyone is on weight loss drugs? In a world where such medications are normalized, fast-food/processed-food companies might just work harder to make their products more addictive…

Seems like all the incentives have been in place for us to have already maximized food addictiveness. We have to at least be pretty far up the S curve. I’d guess just the opposite actually, that companies will refocus on the healthfulness of their products now that customers aren’t as susceptible to the addictive aspects.
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