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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#161
post #56

I’m just as curious as to why some people are so willing to take numerous medications, while others go to any lengths to avoid them. Some people are happy to be on an SSRI, sleeping pill, statin, low dose aspirin, and a few others, and aren’t bothered by this. Other people seem instinctively revolted by prescription drugs, seeing toxins pushed by evil corporations. Is it a trust issue? I personally detest and avoid a…

> Other people seem instinctively revolted by prescription drugs, seeing toxins pushed by evil corporations.

You can advertise drugs on TV in the USA. This certainly opens the door for bad drugs to get pushed out and marketed to people who don't have the technical skills to examine the claims and the risks of side effects objectively.

> avoid all medicines other than antibiotics and vaccines

Just because it's been such a hobby horse lately I would have to add pain killers. There is absolutely a large potential for abuse but they also serve an incredible utility to modern medical care.

> Regularly consuming anything else is an abberration and self-experiment.

Ozempic should be for people who are obese and have thoroughly demonstrated that they are not physically capable of exercising themselves enough to lose weight naturally.

Otherwise, this drug gets marketed as an obesity cure, but it's mostly dispensed for cosmetic purposes. If there are any side-effects, it will be a double tragedy for these people.

I'm with you, it's a little revolting, this specific drug.

Re: How long til we're all on Ozempic?

#162
post #56

I’m just as curious as to why some people are so willing to take numerous medications, while others go to any lengths to avoid them. Some people are happy to be on an SSRI, sleeping pill, statin, low dose aspirin, and a few others, and aren’t bothered by this. Other people seem instinctively revolted by prescription drugs, seeing toxins pushed by evil corporations. Is it a trust issue? I personally detest and avoid a…

Nobody ever gets sus about needing to take heart medication every day to stay alive but the moment it becomes about how I take Lexapro every day they get real preachy.

Which is sorta funny because some antihypertensives are known to decrease anxiety.

Re: How long til we're all on Ozempic?

#163
post #34

My biggest fear is either there will be long term negative consequences to Ozempic et al, and a huge swath of the population will be dealing with issues 30 years form now - OR - there will be some long term positive consequence to using Ozempic et al, and I'm not getting any of the benefits because I'm not overweight.

Keep in mind a lot of people who'd benefit from this may not last another 30 years due to age or health issues due to weight either.

[dead]

Re: How long til we're all on Ozempic?

#164

Earlier quoted context omitted.

Has there ever been a case where something like #2 has happened? Don't think you need to worry about that one.

https://en.wikipedia.org/wiki/Water_fluoridation

Not sure that’s apples to apples. Fluoride is a mineral. IIRC, ozempic is closer to a hormone.

Re: How long til we're all on Ozempic?

#165
post #138

Earlier quoted context omitted.

> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…

>>>Studies show it just doesn't work. It's not that "eat less and exercise more" doesn't work, it's that nobody does it, because it's really, really hard. Calories in/Calories out is both completely true and completely useless for actual humans. edit: that's unfair, mostly useless

The best way to stop smoking is to never have another cigarette!

Re: How long til we're all on Ozempic?

#166

My pet crackpot theory is that within the next 100 years semaglutide is going to be in the drinking water (much like fluoride) because the benefit to society is going to be too hard to pass up on. However, it seems that it's delivered via injection so maybe putting it in the water supply wouldn't even be effective.

I don't think anything that can influence our choices would ever get enough public approval for that.

Re: How long til we're all on Ozempic?

#167

I'd think it more likely that it'll be one of the next generation drugs, but I do agree with the premise that it will be really common. A few weeks ago I started a low dose of tirzepatide (aka Mounjaro, aka Zepbound) and the side effects are interesting. The biggest negative, which just takes adjustment, is drastically lower stomach capacity. Used to be that two eggs and two pieces of toast was breakfast. Now I bette…

> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…

Are there any studies that look at body fat % instead of weight? I don't care how much I weigh.

Re: How long til we're all on Ozempic?

#168

Earlier quoted context omitted.

Well, the negative consequence on the value of willpower is pretty obvious. "In what measure" is the real question.

You know the way that software bloat expands to consume increased computational speed? We're about to see the nutritional equivalent.

I don't understand how that analogy is supposed to work, given that the basic mechanism of these drugs is to reduce appetite (and possibly just desire in general).

Re: How long til we're all on Ozempic?

#169
post #138

Earlier quoted context omitted.

> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…

>>>Studies show it just doesn't work. It's not that "eat less and exercise more" doesn't work, it's that nobody does it, because it's really, really hard. Calories in/Calories out is both completely true and completely useless for actual humans. edit: that's unfair, mostly useless

>It's not that "eat less and exercise more" doesn't work, it's that nobody does it

There are plenty of examples of people who've managed to lose weight through diet and exercise, it's not "nobody". Sure it's a small % success rate, but that's because it's not easy. Just like squatting or deadlifting 300 lbs, it's not easy to get there, but the vast majority of humans could if they decided to put the time and effort into it.

Re: How long til we're all on Ozempic?

#170
Instead of a system that makes these drug available for purchase, I'd rather live in a system that promotes healthy food and active behavior. Unfortunately, I have to drive everywhere, work too many hours to have free time for recreation and have no idea which government subsidy is going to help big ag likely at the expense of my health.

All things being equal, I'd prefer to spend less money on prescriptions and have fewer trips to the doctor.

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