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How long til we're all on Ozempic?

asteriskmag.com

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Re: How long til we're all on Ozempic?

#12

Statins are regularly given to people with high cholesterol. I would bet that most older people take or qualify to take a statin. If it happens with statins, therefore, it's not out of the realm to think that most people will eventually be prescribed GLP-1 to reduce weight which will improve overall health. It makes sense.

Statins have gone through several prescribing guideline revisions in the last 10-20 years. Many people were incorrectly prescribed them and some have suffered for it.

Likewise, there can be serious complications when taking GLP-1 agonists and the like. Since they need to be taken in perpetuity (many gain all weight lost upon stopping use) they should be reserved for only people who have exhausted all other opportunities.

Most people over 65 should not be on statins. Most people should not be taking GPL-1 agonists.

Re: How long til we're all on Ozempic?

#13
There's some evidence that Ozempic improves general impulse control, e.g decreasing alcohol consumption [0], which the article mentions.

Also, as Tyler Cowen writes [1], this is probably going to translate into big improvements for animal welfare:

> People lose weight on these drugs because they eat less, and eating less usually means eating less meat. And less meat consumption results in less factory farming. This should count as a major victory for animal welfare advocates, even though it did not come about through their efforts. No one had to be converted to vegetarianism, and since these drugs offer other benefits, this change in the equilibrium is self-sustaining and likely to grow considerably.

So overall, widespread Ozempic adoption seems like progress to me.

[0] https://www.npr.org/sections/health-shots/2023/08/28/1194526...

[1] https://www.bloomberg.com/opinion/articles/2024-07-20/animal...

Re: How long til we're all on Ozempic?

#14

FWIW, I was prescribed a GLP-1, but my insurance will not cover it. It's incredibly expensive out of pocket.

Only in the US. Other countries are like 90% less expensive. However, Medicare might try to get better deal since the next round of deal making can include it since the drug is 7 years old.

https://slate.com/technology/2023/07/ozempic-costs-a-lot-it-...

Re: How long til we're all on Ozempic?

#15
post #4

It's a pretty sad thought that everybody will be on a drug that keeps weight in check while most people will still eat a basically toxic diet. Weight is certainly an important factor but there is more to a healthy life.

Seems like just an orthogonal problem? If calorie input is solved, now all the moralizing and shaming can be about nutrition instead

Re: How long til we're all on Ozempic?

#17
I don’t want this to come out insensitive or from under the rock, but why is taking a drug a novel & cool idea (all of a sudden/recently) as opposed to good old fashioned working out and not eating more than what you need? okay, this drug is all kinds of great and it’s the next best thing since green grapes, still not eating more and workout is better than taking drugs that effect your brain right? Are doctors required to explain this before prescribing this in US?

Re: How long til we're all on Ozempic?

#18
post #4

It's a pretty sad thought that everybody will be on a drug that keeps weight in check while most people will still eat a basically toxic diet. Weight is certainly an important factor but there is more to a healthy life.

Sure, but the "unhealthy but not excessively caloric" diet is not a problem ozempic attempts to address. As far as I understand, it simply limits your appetite. Potentially one can go on ozempic, lose weight, and still end up eating unhealthily, because the resulting diet is made up of nutritionally poor foods.

Re: How long til we're all on Ozempic?

#19
This article seems to frame things in such a strange way. Maybe instead of trying to get everyone obesity medication, we can instead educate society so we all understand nutrition and diet and can combat the ever-persistent forces of corporations pushing unhealthy food on us?

Re: How long til we're all on Ozempic?

#20

for those that do not know there is a herb that targets GLP-1...its called Berberine And yes its over the counter....I currently take one dose per day at 1200mg

Source? https://www.mcgill.ca/oss/article/medical-critical-thinking/... (2023) disagrees with you:

> Neither is berberine any version of Ozempic, which is an analogue of glucagon-like-peptide-1 (GLP-1), a natural hormone that regulates blood sugar and helps people feel full. Berberine has nothing to do with GLP-1.

> Perhaps the most interesting laboratory finding, given the rising global tide of type 2 diabetes, is the control that berberine may exert over blood sugar. But there is a problem. Berberine is virtually insoluble in water and has low intestinal absorption which means it has poor bioavailability. […] Because of berberine’s poor bioavailability, supplements on the market are likely to be useless. However, some derivative of berberine, may yet make it to the physician’s prescription pad. But it won’t be for weight loss.

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