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Chemistry Nobel: Computational protein design and protein structure prediction

nobelprize.org

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Re: Chemistry Nobel: Computational protein design and protein structure prediction

#41

Post by t_mann »

DevX101 wrote: post #24

Here's a direct quote from the Alphafold paper: "These authors contributed equally: John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Demis Hassabis"

Here's 8 densely printed pages of contributors to a discovery that lead to a Nobel prize:

https://arxiv.org/pdf/1207.7214#page=26

Guess how many of them were included in the prize. It's a shame that the Nobel committee shies away from awarding it to institutions, but the AlphaFold prize doesn't even make the top 10 in a list of most controversial omissions from a Nobel prize. It's a simple case of lab director gets the most credit.

Re: Chemistry Nobel: Computational protein design and protein structure prediction

#43

Post by onursurme »

seydor wrote: post #35
DevX101 wrote: post #24

Here's a direct quote from the Alphafold paper: "These authors contributed equally: John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Demis Hassabis"

They didnt give the award to the paper

The paper represents the work which lead to the prize.

if A=B and A=C, then A=C

Re: Chemistry Nobel: Computational protein design and protein structure prediction

#47

Post by cowsandmilk »

paulwetzel wrote: post #4

While I am skeptical about yesterdays award in physics, these are totally deserved and spot on. There are few approaches that will accelerate the field of drug development and chemistry as a whole in a way that the works of these three people will. Congratulations!

Both Rosetta and DeepMind have made contributions outside of protein structure prediction that are far more important for drug discovery.

Re: Chemistry Nobel: Computational protein design and protein structure prediction

#48

Post by stenl »

DevX101 wrote: post #24

Here's a direct quote from the Alphafold paper: "These authors contributed equally: John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Demis Hassabis"

And further down: ” Contributions

J.J. and D.H. led the research. J.J., R.E., A. Pritzel, M.F., O.R., R.B., A. Potapenko, S.A.A.K., B.R.-P., J.A., M.P., T. Berghammer and O.V. developed the neural network architecture and training. T.G., A.Ž., K.T., R.B., A.B., R.E., A.J.B., A.C., S.N., R.J., D.R., M.Z. and S.B. developed the data, analytics and inference systems. D.H., K.K., P.K., C.M. and E.C. managed the research. T.G. led the technical platform. P.K., A.W.S., K.K., O.V., D.S., S.P. and T. Back contributed technical advice and ideas. M.S. created the BFD genomics database and provided technical assistance on HHBlits. D.H., R.E., A.W.S. and K.K. conceived the AlphaFold project. J.J., R.E. and A.W.S. conceived the end-to-end approach. J.J., A. Pritzel, O.R., A. Potapenko, R.E., M.F., T.G., K.T., C.M. and D.H. wrote the paper.”

Re: Chemistry Nobel: Computational protein design and protein structure prediction

#49

Post by SkiFire13 »

onursurme wrote: post #43
seydor wrote: post #35

Earlier quoted context omitted.

They didnt give the award to the paper

The paper represents the work which lead to the prize. if A=B and A=C, then A=C

> if A=B and A=C, then A=C

Technically true, but you might still want to double check your logic.

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