GLP-1 pills are coming, and they could revolutionize weight-loss treatment

Post by bossyTeacher » Tue, Oct 08, 2024, 4:55 PM UTC

nkohari wrote: post #68

bossyTeacher wrote: post #46

Earlier quoted context omitted.

Sounds worrying to me as it means this is essentially a lifetime drug. As soon as you stop taking it, your appetite returns and so does your old weight. The better option seems to be face the appetite head on rather than putting it on a temporal cage

> Sounds worrying to me as it means this is essentially a lifetime drug. As soon as you stop taking it, your appetite returns and so does your old weight. I see this said all the time about GLP-1 agonists, and it's a mischaracterization. It is true that when you stop taking the drug, your appetite is no longer suppressed, but you can still keep the weight off by eating a sustainable amount of calories. Usually, the b…

Post by andrewmcwatters » Tue, Oct 08, 2024, 5:16 PM UTC

vundercind wrote: post #61

andrewmcwatters wrote: post #12

GLP-1 freaks me out after I read from plastic surgeons that it ages your skin from the inside out.

Plastic surgeons and cosmetic companies are rushing to convince people that the same effects you see from any weight loss are worse with GLP-1 agonists, to court a market with demonstrated willingness to spend money on (among other things) their looks. Plastic surgeons, I expect, are especially concerned about a large reduction in volume of lipo & related procedures, and are eager to get the message out that “no, you…

Post by dang » Tue, Oct 08, 2024, 5:22 PM UTC

thefz wrote: post #102

frankzander wrote: post #47

But why? Just eat no crap and work out. This is long lasting if it's a full life change.

[flagged]

Post by lostmsu » Tue, Oct 08, 2024, 5:25 PM UTC

bossyTeacher wrote: post #100

JumpCrisscross wrote: post #67

Earlier quoted context omitted.

> Diet and exercise don't have negative side effects and they are free They're absolutely not free. They fail at a high rate, which incurs medical costs. And when they work, they require--in practice--a lot of follow-up and coaching. It's fairy-tale level mindblowing that we can look at the status quo where nearly half of the industrialised world is obese and get haughty about a drug that medically, demonstrably impr…

Tell me how much does it cost to do push ups? How much does it cost to do squats? Failing at doing any of these does not incur medical costs. And yes, it takes effort and willpower (like anything worthwile in this life). But none of those cost money. It's fairy-tale level mindblowing that we can look at the status quo where nearly half of the industrialised world is obese and get haughty about a free method (see phys…

Post by r00fus » Tue, Oct 08, 2024, 5:46 PM UTC

petesergeant wrote: post #18

swyx wrote: post #4

for those who are interested in a cheaper, partially generic, pill based option for weight loss, i was just referred by a friend to the naltrexone + bupropion + metformin solution offered by hims (not linking because their website is terrible for learning anything without giving all your health info). he lost 30lbs in 3 months on it. i've just started so i cant vouch but just sharing that non GLP1 appetite suppressio…

This is sold as Contrave / MySimba, albeit adding metformin to the mix is a little unusual https://en.m.wikipedia.org/wiki/Naltrexone/bupropion