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GLP-1 pills are coming, and they could revolutionize weight-loss treatment

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21–30 of 137 posts

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#21

Overconsumption leading to widespread obesity while a large fraction of the world is hungry - the capitalist solution? Let's invent a pill so we can eat EVEN MORE.

This is the opposite of that. It's an appetite suppressant so you eat less, not more.

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#22
post #4

for those who are interested in a cheaper, partially generic, pill based option for weight loss, i was just referred by a friend to the naltrexone + bupropion + metformin solution offered by hims (not linking because their website is terrible for learning anything without giving all your health info). he lost 30lbs in 3 months on it. i've just started so i cant vouch but just sharing that non GLP1 appetite suppressio…

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Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#24
post #3

I'm curious: is the appetite suppressant effect of GLP-1 different from the one from amphetamines?

I can’t speak to amphetamines specifically, but re other stimulants, there’s more of a noticeable fullness effect on GLP-1 meds.

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#25
post #7

Curious if there's been any accounting on the long term impact in terms of cost on the healthcare system. On the one hand, obesity is associated with many other ailments such as heart disease, diabetes, etc. that cost the system a lot of money. On the other hand, well, longer life spans impacting Social Security, Medicare, etc.

??? how is cost on the healthcare system the thing to be worried about over longer lifespan and quality of life? strange thing to focus on lol but i think if you think it thru, 1 should dominate 2, and 2 should be reduced as well.

Are you prepared to make the doctors work for free?

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#26
post #7

Curious if there's been any accounting on the long term impact in terms of cost on the healthcare system. On the one hand, obesity is associated with many other ailments such as heart disease, diabetes, etc. that cost the system a lot of money. On the other hand, well, longer life spans impacting Social Security, Medicare, etc.

??? how is cost on the healthcare system the thing to be worried about over longer lifespan and quality of life? strange thing to focus on lol but i think if you think it thru, 1 should dominate 2, and 2 should be reduced as well.

Because it's literally a large chunk of the economy? Why wouldn't you worry about that. I certainly don't like to see a society where the young are enslaved by the old to pay for their medical treatment.

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#27
post #6

How does it work? Does it reduce the calorie intake by decreasing the appetite? Your body burns more calories because the drug sets the thermostat higher?! Or something else? I don't know how to feel about the idea that we need treatment for being overweight in general.

It patches a reward center in your brain, reducing appetite, but also patching addiction reward center activity. https://recursiveadaptation.com/p/the-growing-scientific-cas... > The consistency that I'm hearing from all across patient groups is gain of control, whereas previously, there was a loss of control… All of a sudden they're able to step back and say, 'oh, well I had this shopping phenomenon that was going o…

Do we know what the long-term affects are? Is there any lasting benefit if someone stops taking these types of medication? If one does keep taking it indefinitely, does the addiction-suppression effect stay the same, or reduces over time?

Re: GLP-1 pills are coming, and they could revolutionize weight-loss treatment

#30

… what? Rybelsus has been out forever. I’ve used it, injected semaglutide, and injected tirzepatide, ama I guess

Did you ever get depression as a side effect?

No, but I take an SSRI for GAD anyway, which might be a confounding factor
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