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Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

nature.com

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Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#11

Post by none4methx »

NavinF wrote: post #5
ggm wrote: post #3

If workable, amazingly cool. I can turn overall 10:00pm and it's stacked zz until 5am. My partner can be hanging on to past midnight and it's pissing her off these last decades. Melatonin gives her horrid florid dreams and restless legs and nobody wants to get hooked to temazepam.

Melatonin usually has no side effects at the correct dosage of 1mg. Was she taking the 10mg costco tablets?

It’s a hormone. Brains are all differently equipped with those so you shouldn’t expect regularity or predictability unless you have a consistent dosage schedule

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#12

Post by NavinF »

none4methx wrote: post #11
NavinF wrote: post #5

Earlier quoted context omitted.

Melatonin usually has no side effects at the correct dosage of 1mg. Was she taking the 10mg costco tablets?

It’s a hormone. Brains are all differently equipped with those so you shouldn’t expect regularity or predictability unless you have a consistent dosage schedule

Dude there have been numerous RCTs. People reported the same side effects for 1mg melatonin and placebo

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#13

Post by mikewarot »

I wonder if Functional Near-infrared cerebral spectroscopy[1] could be used instead of an EEG to make this work, it might be a lot easier, and cheaper... you could sew it all into a hat. Apparently the main thing you need is a Pulse Oxygen Sensor.[2]

[1] https://openfnirs.org/

[2] https://www.analog.com/en/products/max86141.html

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#14

Post by PaulHoule »

NavinF wrote: post #12
none4methx wrote: post #11

Earlier quoted context omitted.

It’s a hormone. Brains are all differently equipped with those so you shouldn’t expect regularity or predictability unless you have a consistent dosage schedule

Dude there have been numerous RCTs. People reported the same side effects for 1mg melatonin and placebo

If I take Melatonin in the usual dose I get St. Elmo’s Fire, no thanks.

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#15

Post by hammyhavoc »

PaulHoule wrote: post #14
NavinF wrote: post #12

Earlier quoted context omitted.

Dude there have been numerous RCTs. People reported the same side effects for 1mg melatonin and placebo

If I take Melatonin in the usual dose I get St. Elmo’s Fire, no thanks.

A literal fungal infection?

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#16

Post by NavinF »

PaulHoule wrote: post #14
NavinF wrote: post #12

Earlier quoted context omitted.

Dude there have been numerous RCTs. People reported the same side effects for 1mg melatonin and placebo

If I take Melatonin in the usual dose I get St. Elmo’s Fire, no thanks.

What's "the usual dose" in mg and wtf is St. Elmo’s Fire?

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#17

Post by PaulHoule »

NavinF wrote: post #16
PaulHoule wrote: post #14

Earlier quoted context omitted.

If I take Melatonin in the usual dose I get St. Elmo’s Fire, no thanks.

What's "the usual dose" in mg and wtf is St. Elmo’s Fire?

What you might get in a supplement, 0.3 mg to 3 mg or so.

It is like the feeling late after an LSD trip maybe 10-12 hours or more after the "usual dose" which would be 80 to 320 mcg.

Sensorium is lit up like a light psychedelic experience, might be weary but complete unable to shut down. In my image of myself in my mind's eye I am glowing with corona discharge.

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#18

Post by blufuz »

mikewarot wrote: post #13

I wonder if Functional Near-infrared cerebral spectroscopy[1] could be used instead of an EEG to make this work, it might be a lot easier, and cheaper... you could sew it all into a hat. Apparently the main thing you need is a Pulse Oxygen Sensor.[2] [1] https://openfnirs.org/ [2] https://www.analog.com/en/products/max86141.html

If you want to target alpha oscillations, fNIRS is not sufficient, it measures oxygenation changes in the blood, which is a delayed metabolic response to brain activity, changing on the scale of seconds. EEG oscillations instead reflect real-time neuronal electrical activity, changing on the scale of tens of milliseconds. On the plus side, you can also sew EEG into headbands, there are a lot of wearable devices under development.

Re: Α phase-locked auditory stimulation to treat symptoms of sleep onset insomnia

#19

Post by NavinF »

PaulHoule wrote: post #17
NavinF wrote: post #16

Earlier quoted context omitted.

What's "the usual dose" in mg and wtf is St. Elmo’s Fire?

What you might get in a supplement, 0.3 mg to 3 mg or so. It is like the feeling late after an LSD trip maybe 10-12 hours or more after the "usual dose" which would be 80 to 320 mcg. Sensorium is lit up like a light psychedelic experience, might be weary but complete unable to shut down. In my image of myself in my mind's eye I am glowing with corona discharge.

Wow that's unique! I wonder if there are any other people that respond like that
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