These sorts of articles raise so many thoughts and emotions in me. I was trained as a computational biologist with a little lab work and ran gels from time to time. Personally, I hated gels- they're finicky, messy, ugly, and don't really tell you very much. But molecular biology as a field runs on gels- it's the priimary source of results for almost everything in molbio. I have seen more talks and papers that rested…
Similar - when I was younger, I would never have suspected that a scientist was committing fraud. As I've gotten older, I understand that Charlie Munger's observation "“Show me the incentive and I will show you the outcome.” is applicable everywhere - including science. Academic scientists' careers are driven by publishing, citations and impact. Arguably some have figured how to game the system to advance their caree…
In my relatively short career, I have been asked to manipulate results several times. I refused, but this took an immense toll, especially on two occasions. Some people working with me wanted to support me fighting dishonesty. But guess what, they all had families and careers and were ultimately not willing to do anything as this could jeopardize their position.
I've also witnessed first-hand how people that manage to publish well adopt monopolistic strategies, sabotaging interesting grant proposals from other groups or stalling their article submissions while they copy them. This is a problem that seldomly gets discussed. The current review system favors mono-cultures and winner-takes-it-all scenarios.
For these reasons, I think industrial labs will be doing much better. Incentives there are not that perverse.