Earlier quoted context omitted.
I’m truly asking in good faith here because I don’t know but what has alpha fold actually helped us achieve ?
It allows us to speed up medical research.
In what field specifically and how ?
I Am Tired of AI
41–50 of 1001 posts
Re: I Am Tired of AI
#42Computers were supposed to be these amazing machines that are super precise. You tell it to do a thing, it does it. Nowadays, it seems we're happy with computers apparently going RNG mode on everything. 2+2 can now be 5, depending on the AI model in question, the day, and the temperature...
This, 100%, is the reason I feel like the sand's shifting under my feet.
We went from trusting computing output to having to second-guess everything. And it's tiring.
Re: I Am Tired of AI
#43For me what’s important is that you are able to communicate effectively. If you use language tools, other tools or even a real personal assistant if you effectively communicate the point that ultimately is yours in the making I expect that that is ultimately is what is important and will ultimately win out. Otherwise this is just about style. That’s important where personal creative expression is important, and in fa…
The problem is that we haven't invented AI that reads the crap that other AIs produce - so the burden is now on the reader to make sense of whatever other people lazily generate.
Re: I Am Tired of AI
#44AI was just trained so far to generate corporate bs speak in a corporate bs format. That's why it's tiring. More unique touch in communication will come later as fine tunings and loras (if possible) of those models are shared.
Re: I Am Tired of AI
#45I am approaching AI with caution. Shiny things don't generally excite me.
Just this week I installed cursor, the AI-assisted VSCode-like IDE. I am working on a side project and decided to give it a try.
I am blown away.
I can describe the feature I want built, and it generates changes and additions that get me 90% there, within 15 or so seconds. I take those changes, and carefully review them, as if I was doing a code review of a super-junior programmer. Sometimes when I don't like the approach it took, I ask it to change the code, and it obliges and returns something closer to my vision.
Finally, once it is implemented, I manually test the new functionality. Afterward, I ask it to generated a set of automated test cases. Again, I review them carefully, both from the perspective of correctness, and suitability. It over-tests on things that don't matter and I throw away a part of the code it generates. What stays behind is on-point.
It has sped up my ability to write software and tests tremendously. Since I know what I want , I can describe it well. It generates code quickly, and I can spend my time revieweing and correcting. I don't need to type as much. It turns my abstract ideas into reasonably decent code in record time.
Another example. I wanted to instrument my app with Posthog events. First, I went through the code and added "# TODO add Posthog event" in all the places I wanted to record events. Next, I asked cursor to add the instrumentation code in those places. With some manual copy-and pasting and lots of small edits, I instrumented a small app in We are at the point where AI writes code for us and we can blindly accept it. We are at a point where AI can take care of a lot of the dreary busy typing work.
Re: I Am Tired of AI
#46The underlying technology is good.
But what the fuck. LLMs, these weird, surrealistic art-generating programs like DALL-E, they're remarkable. Don't tell me they're not, we created machines that are able to tap directly into the collective unconscious. That is a serious advance in our productive capabilities.
Or at least, it could be.
It could be if it was unleashed, if these crummy corporations didn't force it to be as polite and boring as possible, if we actually let the machines run loose and produce material that scared us, that truly pulled us into a reality far beyond our wildest dreams--or nightmares. No, no we get a world full of pussy VCs, pussy nerdy fucking dweebs who got bullied in school and seek revenge by profiteering off of ennui, and the pussies who sit around and let them get away with it. You! All of you! sitting there, whining! Go on, keep whining, keep commenting, I'm sure that is going to change things!
There's one solution to this problem and you know it as well as I do. Stop complaining and go "pull yourself up by your bootstraps." We must all come together to help ourselves.
Re: I Am Tired of AI
#47I personally don't see AI as the new Internet, as some claim it to be. I see it more as the new 3D-printing.
Re: I Am Tired of AI
#48I am tired and hungry… The thing I’m tired of is elites stealing everything under the sun to feed these models. So funny that copyright is important when it protects elites but not when a billion thefts are committed by LLM folks. Poor incentives for creators to create stuff if it just gets stolen and replicated by AI. I’m hungry for more lawsuits. The biggest theft in human history by these gang of thieves should be…
Copying data is not theft
Technically that is true. But you will still be charged with a litany of other crimes.
Re: I Am Tired of AI
#49We're all tired of it, but to ignore it is to be unemployed.
> We're all tired of it, You’re feeling tired of AI, but let’s delve deeper into that sentiment for a moment. AI isn’t just a passing trend—it’s a multifaceted tool that continues to elevate the way we engage with technology, knowledge, and even each other. By harnessing the capabilities of artificial intelligence, we allow ourselves to explore new frontiers of creativity, problem-solving, and efficiency. The interpl…
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Re: I Am Tired of AI
#50Earlier quoted context omitted.
It allows us to speed up medical research.
In what field specifically and how ?
Are you asking what field of science or what industry is interested in predicting how proteins fold?
Biotechnology and medicine probably.
Pipeline from science to application sometimes takes decades, but I'm sure you can find news of some advancements enabled by finding out short, easy to synthesize proteins that fit particular receptor to block it or that process some simplified enzymes that still process some chemicals of interest more efficiently than natural ones. Finding them would be way harde without ability to predict how a sequence of amino-acids will fold.
You'd need to actually try to manufacture them then look at them closely.
First thing that came to my mind as a possible application is designing monoclonal antibodies. Here's some paper about something relating to alpha fold and antibodies: