131–140 of 148 posts
Does anyone have personal experience or an understanding of why sometimes coffee in the afternoon actually results in a feeling of perceived tiredness?
Earlier quoted context omitted.
Oh wow, I'm surprised that this is not common knowledge given how common coffee is. I didn't even know it was a thing. File me under "A cup of coffee feels like a small dose of MDMA"
Lucky you! LOL. Hope it doesnt come with the nasty comedown :P
I can't have coffee multiple days in a row, else I'll experience panic attacks (and in that moment i think I'm going to die, nearly reaching for a phone to call 911). And can't partake in coffee ~95% of the time (friends don't have decaf, a ton of nicer coffee shops don't either, and often decaf is neglected so i'm drinking black water). I still love the taste of coffee, so i've kinda been robbed of that unless i'm at home and can make it myself.
I had a >300mg caffeine/day energy drink habit for a few of years. It took around six months to get past the additional fatigue after quiting. There seems to be some long term effect on me way beyond the half life. Does everyone else get past the effects of going cold turkey in a matter of hours?
Earlier quoted context omitted.
I think the point is to prevent the data from being linked to your identify (name, address etc.).
Your identity can be reconstructed from relative's samples. If you submit your sequence its out of your hands forever. The only way to do this privately is to do the sequencing in your own lab.
Earlier quoted context omitted.
You might try slow release melatonin. I've found melatonin increases the vividness of dreaming, though.
Or reduce the dosage. I've had much better sleep on 1mg than the 3+ mg you find most places.
https://www.lesswrong.com/posts/E4cKD9iTWHaE7f3AJ/melatonin-...
To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
Is the "Ultra Deep" analysis worth it over the standard "Deep" analysis?
Earlier quoted context omitted.
Your identity can be reconstructed from relative's samples. If you submit your sequence its out of your hands forever. The only way to do this privately is to do the sequencing in your own lab.
I sequence my own genome in my own private lab. At least weekly. The rush when the sequencing begins. I almost can't help but sequence all over the place.
To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
When I think about sequencing, I think about verifiability. With anonymity blinkers on, you could give me several gigabytes of random data and I'd have limited recourse. Will Nebula give me an intelligible whole-genome data file if I happen to be a Golden Retriever?
I know from my clinical history that I have mutations in the UGT1A1 gene that cause me to metabolize bilirubin differently. That is a relatively common mutation that occurs in roughly 2-3 percent of people. Unless I am lucky enough to have a random result that coincides with this, I could be fairly certain that this data is somewhat reliable. The problem thought, I don't know the degree of reliability.
I had a >300mg caffeine/day energy drink habit for a few of years. It took around six months to get past the additional fatigue after quiting. There seems to be some long term effect on me way beyond the half life. Does everyone else get past the effects of going cold turkey in a matter of hours?