121–130 of 148 posts
To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
I had a similar idea to track my caffeine intake(assuming that the half-life is 6 hours). The only question I haven't had time to look into yet is what is the biological effect of previously taken vs newly taken caffeine? Say I had a cup of coffee at 9 am and then have another one at 9+6 hours=3 pm. Assume that 1 cup of coffee has 90 mg of caffeine. Does it mean that at that moment, I will have to track 2 different h…
Quitting caffeine was one of the best health decisions I've ever made. My sleep is much better and I have just way more energy in general than when I was a heavy coffee drinker. The craziest thing is now when I wake up in the morning... I'm just awake. There is no groggy pre-coffee malaise.
As a heavy caffeine consumer since at least middle school (I'm 37 currently): consider why you're wanting so much and maybe talk to your doctor about it. Turns out I was dealing with ADHD probably my whole life and caffeine abuse was a cope.
Though ADHD meds tend to have even more extreme physiological effects on the body than a bunch of caffeine. But at least, in return, they work.
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Actually went through fullgenomes.com - they apparently don't offer exome sequencing any more but for under $1200 getting your genome sequenced is interesting. If you ask anyone who works in genetics, though, they'll advise you never to do it. It can be bad news, but there's virtually no good news there.
I had mine run twice through 23andMe just to make sure they didn’t get something wrong. I tried to get my full genome once but the company screwed me over. And I take exception to your “no good news”. I discovered a gene polymorphism that led to the discovery the reason for my immune deficiency and mood disorder. I found it gave me agency as well since I know that these genes are all risk genes and not fully determin…
I would regard that as one of the exceptions in the "virtually no" caveat.
Quitting caffeine was one of the best health decisions I've ever made. My sleep is much better and I have just way more energy in general than when I was a heavy coffee drinker. The craziest thing is now when I wake up in the morning... I'm just awake. There is no groggy pre-coffee malaise.
How long did it take to not wake up groggy?
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Measure your blood pressure. Measure before consumption. Take three different readings. Measure at one hour intervals after caffeine consumption. Fast metabolizers BP should return to baseline within a couple of hours. Mine would remain elevated for 10-12 hours.
Did you measure your baseline blood pressure without caffeine as well?
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Oh wow, I'm surprised that this is not common knowledge given how common coffee is. I didn't even know it was a thing. File me under "A cup of coffee feels like a small dose of MDMA"
For anyone else who discovers they are a fast metabolizer of coffee: try eating a big breakfast before drinking coffee to slow absorption. I wanted to be a coffee drinker for YEARS, but it made me really high, and I felt super tired later in the day. I don't know why I didn't connect the dots until I searched my genome, but once you know whether you are a fast or slow metabolizer you can play all sorts of games. I ca…