In my many years of consuming many drugs, no rule is more obvious than the fact that each person responds to different drugs differently, develops tolerances differently and develops addictions differently. The only way to understand drugs is to start from the position that my experience and your experience are almost certain to be different.
Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
111–120 of 148 posts
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#112Quitting caffeine was one of the best health decisions I've ever made. My sleep is much better and I have just way more energy in general than when I was a heavy coffee drinker. The craziest thing is now when I wake up in the morning... I'm just awake. There is no groggy pre-coffee malaise.
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#113Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#114To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
nebula genomics uses chinese labs - would be careful about your data
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#115Please take in to account slow vs fast caffeine metabolizer. "CYP1A2 Gene: Fast or Slow Caffeine Metabolizer?" https://www.geneticlifehacks.com/liver-detox-genes-cyp1a2/ This is one of those subjects where people argue past each "I can drink a cup of coffee and sleep like a baby!" vs "One cup of coffee in the morning and my sleep quality is impacted". And neither understands how the other can have a vastly different…
Also needs to take into account if/when you're exposed to nicotine since nicotine can affect caffeine metabolism by CYP1A2 depending on your genotype.
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#116Does anyone have personal experience or an understanding of why sometimes coffee in the afternoon actually results in a feeling of perceived tiredness?
Have you tried a "coffee nap"? I find that if I just drink caffeine to counteract building tiredness, it's not going to help. Like sponging up water from a broken faucet. But if I lay down and rest (this doesn't have to include sleep, I set an alarm and let my body do what it needs, but the primary factor is giving your brain the peace it needs to process and flush stress accumulated through the day, in pseudoscientific terms), and then drink coffee, I'm reset and it can take effect.
The "Coffee Nap" is where your drink a cup of coffee (quickly, I guess), then lay down for 10-20 minutes to rest, and by the time you get up the caffeine will begin to kick in. I find that process to be a bit more stress-inducing.
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#117This is innovation
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#118To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
Do you have other alternatives which are more privacy preserving? The last time I heard about 23andMe was here in HN [1].
[1] https://hn.algolia.com/?dateRange=pastWeek&page=0&prefix=fal...
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#119Does anyone have personal experience or an understanding of why sometimes coffee in the afternoon actually results in a feeling of perceived tiredness?
From what I understand (I'm not a scientist), caffeine doesn't "give" you energy, but rather makes your body ignore the tiredness , by turning off some of the machinery that would make you feel tired. By having coffee in the morning and then in the afternoon, you build a "high" of caffeine that forces most of your "alert systems" to shut down. Once the peak wears off though, your body starts remembering to alert you…
> From what I understand (I'm not a scientist), caffeine doesn't "give" you energy, but rather makes your body ignore the tiredness, by turning off some of the machinery that would make you feel tired.
I have heard this too, but it doesn't feel like this to me, it feels like a stimulant getting me to a state above and beyond the one I would be in without the caffeine. There are also a lot of references to caffeine as a stimulant. So what is really going on?
Re: Coffee Stats – Maximize Caffeine Intake and Get to Bed at Night
#120To determine whether you're a slow or fast caffeine metabolizer.. Wait for a sale at Nebula.org. Get your whole genome sequenced. ~$200. Having your whole genome sequenced could have added benefits down the road. Download the .BAM file. It will be several gigabytes. Use WSG Extract to generate the 23andMe raw data files. https://www.geneticlifehacks.com/convert-whole-genome-file/ Connect that data file to Genetic Lif…
nebula genomics uses chinese labs - would be careful about your data
Why?