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Researchers find Alzheimer's-like brain changes in long Covid patients

uknow.uky.edu

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Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#171

Post by 93n »

BaculumMeumEst wrote: post #132
BaculumMeumEst wrote: post #40

Fuck, I recently had Covid and I've been having trouble recalling things. Every other day or so I'll spend 5-10 seconds remembering the name of something. It's possible this happened before I got Covid, though... I don't remember!

Wait, no, false alarm. I remember this happened before COVID. The first thing I remember having trouble remembering was the name of the game "Signalis". That was like a year ago. I'm mid thirties. So it's not COVID, I'm just demented. What a relief!! I should play Signalis again...

Late 20s, same thing. I am constantly forgetting words for things, but can visualize what it's describing in my head.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#172

Post by phkahler »

refulgentis wrote: post #14
phkahler wrote: post #5

[flagged]

The spike is a sigil that induces a cell to say "Oh cool! You have the ACE2 passcode! Let me inject you into me, virus!" A replica of a key doesn't start a car: you need an engine too.

No, the spike proteins have been shown to do damage. They aren't just a key. And yeah sorry I don't have a reference, I quit even thinking about Covid after my 3rd round.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#173

Post by tim333 »

xyst wrote: post #18

Today’s generations just do not get a break. Brain rot in the form of social media. Cognitive decline from possible long COVID. Constant exposure to microplastics from various sources (water contamination, water bottles, plastic wrapping, cars via tire breakdown). This timeline fucking sucks.

On the other hand, singularity type stuff.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#174

Post by tim333 »

findthewords wrote: post #6

Alz is brain inflammatory response to viruses (among other foreing detritus) that got past the blood-brain barrier, so I'm not surprised.

A problem with that hypothesis is that Alzheimer's is very much found amongst the elderly while virus attacks hit all ages. Not saying that isn't involved but there's more to it.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#175

Post by NemoNobody »

lol768 wrote: post #49
OJFord wrote: post #41

Earlier quoted context omitted.

I mean when you write 'UK researchers find', especially to a global audience (which UoKentucky PR dept may not particularly have but HN does (Hello from the ( the !) UK)) that it sounds more like the country UK than the.. no offence intended but not exactly world renowned university. (I've heard of Kentucky, probably my first time hearing of its university in its own right - though I might have assumed it had one.)

It seems like a fairly mediocre institution, at least in terms of research output: https://www.nature.com/nature-index/institution-outputs/gene... Not entirely surprised we'd never heard of it.

I don't feel like that is a correct way to measure an institutions mediocrity or not. I have found that frequently cited Universities that publish many very popular articles per year per journal become less credible with fame. Hubris aside objectivity becomes lost in the money being made.

A far better measure of a University would be the people it graduates or by assessing the actual effects and impact of a research University with their published studies.

If the University of Kentucky specializes in agricultural research, that's most likely why you've never heard of them - perhaps they've made huge contributions to the elimination of terrible fungus plaguing a specific crop, nobody would hear about that.

Fixing the proverbial fungus is a far bigger deal tho than most of the ambiguous pop science publications coming out of far more "prestigious" institutions these days.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#176

Post by BaculumMeumEst »

93n wrote: post #171
BaculumMeumEst wrote: post #132

Earlier quoted context omitted.

Wait, no, false alarm. I remember this happened before COVID. The first thing I remember having trouble remembering was the name of the game "Signalis". That was like a year ago. I'm mid thirties. So it's not COVID, I'm just demented. What a relief!! I should play Signalis again...

Late 20s, same thing. I am constantly forgetting words for things, but can visualize what it's describing in my head.

My wife says the same for her. I think we all just have stressful jobs and are cramming tons of information into our brains. Something's gotta give!

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#177

Post by vaidhy »

patrickdavey wrote: post #113

I visited two friends recently when I was back in Ireland. They had both been fit climber/orienteering types. Both now incapacitated with long covid. Both had been vaccinated. I went for a very short very slow walk with one of them. She wears a fancy Garmin which beeps when her heart rate goes over 100bpm. We walked for 15 mins and it went off. I really hadn't realised quite how real and quite how incapacitating long…

More of a pedantic nitpick - but 100 bpm is still zone 1 for most people.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#178

Post by mikewarot »

I've often said that I feel like I've lost at least a decade off my life. I had Covid back before tests, etc back in March 2020. Lots of testing until I lost my insurance. Recently, my GP says it's probably Long Covid, but we'll never prove it.

Beta blockers seem to have helped a little bit, at least my pulse doesn't just sit at 80 all the time. I find myself angry at getting so little done... until I do something... and then WHAM... that was a mistake.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#179

Post by throwaway_4179 »

stevenalowe wrote: post #167
throwaway_4179 wrote: post #131

Yep. People think I'm exaggerating when I say I've developed dementia. It's pretty intense (and terrifying) on the inside, but I've found ways to compensate to appear vaguely normal on the outside. Look, I'm even using multisyllabic words here! I also have the profound cardiovascular deconditioning described in other comments. So many hopes dreams flushed down the toilet, but people assume that I'm just lazy and stup…

much empathy/sympathy; vascular dysregulation is terrifying, but treatable. cognitivefx.com (in Utah) does excellent work in this area, as do others good luck!

Thanks for the empathy and for the tip!

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#180

Post by AnthonBerg »

bamboozled wrote: post #126
iforgotpassword wrote: post #125

Earlier quoted context omitted.

ME/CFS cases about doubled after covid, and is not even known to be a thing by a lot of doctors. So the symptoms are easily brushed off as "get your shit together" or misdiagnosed as depression. Also your anecdote aligns with the fact that it's more women than men who get it.

I don't want to be rude, but if there is no way of reliably testing for long covid, you might as well say it could be anything, including depression ? How is a doctor, who could see hundreds of patients a week supposed to know ?

I don’t want to be rude, but have you looked into the established scientific knowledge which has accumulated on the impact of SARS-CoV-2 on the human body?

I really truly don’t want to be rude. I only want to point to the existence of literature on this.

There are results from molecular biology, from the various medical specializations, from population-scale studies.

There are certainly symptoms and biomarkers. There are documented changes to physiology, and there exists at least some information on how to help the body recover.

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