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Researchers find Alzheimer's-like brain changes in long Covid patients

uknow.uky.edu

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Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#71

Post by nprateem »

Aurornis wrote: post #51
unyttigfjelltol wrote: post #45

Earlier quoted context omitted.

These days I just blame everything on histomine dysfunction and marvel that the medical complex has been so reluctant to pick it up.[1] [1] https://www.bda.uk.com/resource/caution-advised-with-low-his...

Histamine and MCAS have been adopted by alternative medicine as an explanation for everything, but it’s not supported by science. Dieticians like the one you linked have been coming up with theories for how everything is caused by either too much or too little histamine for years. MCAS is particularly over diagnosed right now. The number of patients who think they have MCAS based on TikTok and Internet forums is so b…

When you get ill and what the doctors give you doesn't work you have to research for yourself. Added to that you wonder if you'll ever get better.

My own research was the only way I got clear of an illness I had after what the doctors gave me didn't work.

It's easy to feel like stupid people are falling for reddit bullshit (and if course some are), but reddit is a potentially huge sample of empirical reports. Even if their reasoning is wrong it doesn't always mean they csn't find cures. That's how we got most medicines in history anyway.

Secondly reddit etc are full of highly motivated, desperate people. You might become one yourself one day too. The saddest part is their illness, not their trying to do something about it.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#72

Post by ETH_start »

The studies purporting to show evidence of long COVID, i.e. long term complications from COVID infections, are notoriously weak on rigor. Most make no attempt to control for the psychosocial impact of positive COVID diagnoses, like the isolation of quarantine, and the anxiety associated with being given a positive diagnosis for the infection.

The best evidence available suggests most cases of "long COVID" are misattribution:

https://jamanetwork.com/journals/jamainternalmedicine/fullar...

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#73

Post by resoluteteeth »

findthewords wrote: post #6

Alz is brain inflammatory response to viruses (among other foreing detritus) that got past the blood-brain barrier, so I'm not surprised.

> Alz is

This one theory that currently doesn't have a lot of hard evidence supporting it. It is a promising theory, but I don't think it is good to state it as if it is established fact.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#74

Post by nradov »

sweeter wrote: post #58
fao_ wrote: post #48

Earlier quoted context omitted.

The reason for that is around 30 - 50 years of continual gutting of the NHS, aggressive implementation of perverse incentives and anti-targets (e.g. "hospitals get less money if they fail to meet X standard of care, because they do not have enough money"), and overloading of staff duties to reduce costs (e.g. Physicians now performing duties that receptionists used to handle, the lack of work force meaning they have…

typical austerity measures. The US and the UK power holders have massive incentives to privatize healthcare and schooling, so they de-fund and starve the beast with the sole purpose of trying to get people to support laws that turn public institutions into private ones. "a government small enough to drown in the bath water" With healthcare this is especially disastrous. In the US for example, most smaller towns don't…

The US healthcare system is generally terrible for cost effectiveness but efficacy is very good for certain things. For most types of cancer, our 5-year survival rates are at or near the top worldwide.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#75

Post by kazinator »

dyauspitr wrote: post #7
School-Cotton wrote: post #3

UK meaning the University of Kentucky, not the United Kingdom.

[flagged]

Researchers are identified by country when their research institution lacks recognition or prestige. If all we know is that someone is a U-of-Kentucky researcher or else that someone is a researcher located in the United Kingdom, the former carries more prestige.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#76

Post by mitthrowaway2 »

wilsonnb3 wrote: post #33
addicted wrote: post #29

Earlier quoted context omitted.

All of this has been true for over half a century. The problem is that the direction of improvement in lives has changed. Compare today to the 90s and there’s very little reason to believe that today is better than the 90s in a developed country. What’s frustrating is that we have MORE tools to be in a much better shape right now. We have things available to us today that people wouldn’t have dreamt of in the 90s, in…

Safer and more reliable cars, cancer is less deadly, the HPV vaccine, malaria vsccines, lower homicide rate, I could go on but this seems like a good list. Be careful where you get your data - news is biased towards sensationalism and negativity.

Cars are getting increasingly dangerous for non-occupants, unfortunately. But certainly AIDS is in a much better situation than it was in the '90s.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#77

Post by speff »

ETH_start wrote: post #72

The studies purporting to show evidence of long COVID, i.e. long term complications from COVID infections, are notoriously weak on rigor. Most make no attempt to control for the psychosocial impact of positive COVID diagnoses, like the isolation of quarantine, and the anxiety associated with being given a positive diagnosis for the infection. The best evidence available suggests most cases of "long COVID" are misattr…

That article is from 2021 when people were just dipping into studying long COVID. If you do a search for the term, there have been multiple studies from this year on the site you're linking characterizing the observed effects of long COVID. And we haven't been in quarantine for a few years now at this point.

https://jamanetwork.com/searchresults?q=long%20covid&allSite...

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#78

Post by add-sub-mul-div »

ljm wrote: post #22
xyst wrote: post #18

Today’s generations just do not get a break. Brain rot in the form of social media. Cognitive decline from possible long COVID. Constant exposure to microplastics from various sources (water contamination, water bottles, plastic wrapping, cars via tire breakdown). This timeline fucking sucks.

On the plus side, we don’t need to worry about spending our lives in an iron lung, smallpox is a non-issue, and in most of the west there isn’t much of a concern about a mother dying giving birth. Hot water can be taken for granted, as can indoor toilets. And central heating. With modern electronics and circuitry you can’t even kill yourself with a toaster in the bathtub since it will trip the central breaker. Every…

We had modern conveniences during recent times before technology and capitalism accelerated into constant predatory bullshit.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#79

Post by hollerith »

Aurornis wrote: post #51
unyttigfjelltol wrote: post #45

Earlier quoted context omitted.

These days I just blame everything on histomine dysfunction and marvel that the medical complex has been so reluctant to pick it up.[1] [1] https://www.bda.uk.com/resource/caution-advised-with-low-his...

Histamine and MCAS have been adopted by alternative medicine as an explanation for everything, but it’s not supported by science. Dieticians like the one you linked have been coming up with theories for how everything is caused by either too much or too little histamine for years. MCAS is particularly over diagnosed right now. The number of patients who think they have MCAS based on TikTok and Internet forums is so b…

You've convinced me that you do not have MCAS.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#80

Post by _DeadFred_ »

addicted wrote: post #29
ljm wrote: post #22

Earlier quoted context omitted.

On the plus side, we don’t need to worry about spending our lives in an iron lung, smallpox is a non-issue, and in most of the west there isn’t much of a concern about a mother dying giving birth. Hot water can be taken for granted, as can indoor toilets. And central heating. With modern electronics and circuitry you can’t even kill yourself with a toaster in the bathtub since it will trip the central breaker. Every…

All of this has been true for over half a century. The problem is that the direction of improvement in lives has changed. Compare today to the 90s and there’s very little reason to believe that today is better than the 90s in a developed country. What’s frustrating is that we have MORE tools to be in a much better shape right now. We have things available to us today that people wouldn’t have dreamt of in the 90s, in…

I disagree. Reagan's plans, including legitimizing stock buybacks which were previously taboo stock manipulation, 'starving the beast' where a political party was willing to weaponize making the US government worse in order to achieve their ends, etc. are what is responsible for today's worsening environment. You are conflating current technical change with the results of decades olds political policies.
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