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WTH Is Cerebrolysin, Actually?

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Re: WTH Is Cerebrolysin, Actually?

#11

Post by jaggederest »

jaggederest wrote: post #9
knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Penicillin, polio vaccine, thorazine, morphine, cisplatin, phenol, arguably semaglutide is the most recent. There have been miracle drugs released every decade or so since the early 1900s. They're just normal now. They stop being a miracle once we're used to them. People used to die of fevers. Of sepsis. And there was nothing that could be done. Let alone cancer.

Oh I forgot about insulin. A little over 1% of the people currently alive would be rapidly dead without it.

Re: WTH Is Cerebrolysin, Actually?

#12

Post by 9dev »

knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Not the answer you’re looking for, but mRNA vaccines as used for COVID are nothing short of a miracle. The bioengineering behind them, the logistics of it all—it was incredible.

Re: WTH Is Cerebrolysin, Actually?

#13

Post by thomasfedb »

knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Paracetamol (acetaminophen) - a fairly effective, synergistic, non-addictive, predictably dosed, analgesic.

Re: WTH Is Cerebrolysin, Actually?

#14

Post by akoboldfrying »

thomasfedb wrote: post #13
knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Paracetamol (acetaminophen) - a fairly effective, synergistic, non-addictive, predictably dosed, analgesic.

Which, TTBOMK, we still don't understand the mechanism of at all. But yes, it's fantastic stuff!

Re: WTH Is Cerebrolysin, Actually?

#15

Post by emsign »

> Ever Pharma’s explanation of how the putative peptides in Cerebrolyin cross the blood-brain barrier does not make sense and flies in the face of scientific research which shows that most peptides do not cross the blood-brain barrier

It can be considered a benefit from a manufacturer's pov that their product doesn't work. If it did their customers would smarten up and stop buying it.

Anyway this looks like your typical "traditional" chinese medicine scam. I mean it has something to do with animal brains, of course it works, right?

Re: WTH Is Cerebrolysin, Actually?

#16

Post by The_Colonel »

thomasfedb wrote: post #13
knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Paracetamol (acetaminophen) - a fairly effective, synergistic, non-addictive, predictably dosed, analgesic.

It's not addictive, but you gain tolerance.

IIRC it's also hard on liver, esp. in combination with alcohol (which js unfortunate since it's otherwise good for hangover).

Re: WTH Is Cerebrolysin, Actually?

#17

Post by A_D_E_P_T »

"“nootropics” users be like: develop never-before-seen prion diseases from Belarusian nootropics made from centrifuged pig brains that you take intravenously but it was all worth it to accomplish great things like posting on an internet messageboard about nootropics"

- The Mighty Hakan

Re: WTH Is Cerebrolysin, Actually?

#18

Post by kev009 »

9dev wrote: post #12
knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

Not the answer you’re looking for, but mRNA vaccines as used for COVID are nothing short of a miracle. The bioengineering behind them, the logistics of it all—it was incredible.

Maybe if it did what they said it would instead of moving the goal posts around to fit what actually happened.

Re: WTH Is Cerebrolysin, Actually?

#19

Post by user_7832 »

nwienert wrote: post #10
knodi123 wrote: post #4

Okay, so this miracle drug isn't a miracle either. Which miracle drug is?!?! I'm not asking sarcastically or ironically- I'm sincerely begging for miracles. Anyone??

GLP-1 agonists. https://www.astralcodexten.com/p/why-does-ozempic-cure-all-d... Beyond their somewhat miraculous effects on obesity, they seem to have a wide variety of positive effects even for non-overweight people. They are likely the best and broadest thing we have for stopping negative addictions. They have incredibly positive effects for immune issues. Plus strong early trial results for Parkinson's, Alzheimers…

What's slightly interesting to me is that some effects of adhd medications (particularly methylphenidate) sound quite similar - it too (can) change motivation regarding food (and actually can make unhealthy donuts seem disgusting) and of course suppresses apptetite (sometimes a little too much). I'd love to know if anyone who's taken both mph & a GLP-1 agonist how similar/different they are.

(There's other interesting aspects of mph too - like how it can change sensitivities - and actually make light mode not feel like your eyes are on fire! - but that's a comment probably for another time.)

Re: WTH Is Cerebrolysin, Actually?

#20

Post by _nalply »

rdtsc wrote: post #2

> Pigs were a fortuitous choice due to the fact that they are especially resistant to prion disease Prions is the first thing that came to mind after reading the description. I had not idea pigs are resistant to it. TIL.

Perhaps. I wouldn't believe any statements that I learnt today before some research validating it, and even then only give a measure of confidency.

Here I did that for you:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510857/

I trust NIH so my confidence that they write corresponds to truth is high even for the scientific interpretation of truth.

And that's what they wrote:

> Pigs were considered prion resistant as no natural cases have been observed despite a large population and being fed intensely with feedstuffs containing animal derived protein. However, it has been demonstrated that BSE is able to infect pigs albeit with low efficiency [...]

So, no, pigs are not resistant but more resistant than cattle and humans.

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