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Ozempic is changing people's skin, say plastic surgeons

allure.com

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Re: Ozempic is changing people's skin, say plastic surgeons

#91

Post by lagichikool »

Faaak wrote: post #45
lagichikool wrote: post #36

Earlier quoted context omitted.

Even coffee is without its downsides and risks. There are cardiovascular risks, acid reflux, sleep issues, and probably more.

I though GERD was not caused by coffee [1]: "Drinking coffee or tea and adding milk or sugar was not associated with reflux symptoms or EE" [1]: https://journals.lww.com/tcmj/_layouts/15/oaks.journals/down...

Certainly is a problem for me and I've seen others say the same. Every doctor I've been to has mentioned it as an issue.

"Caffeine — a major component of many varieties of coffee and tea — has been identified as a possible trigger for heartburn in some people. Caffeine may trigger GERD symptoms because it can relax the lower esophageal sphincter (LES)."

https://www.healthline.com/health/gerd/coffee-tea

Re: Ozempic is changing people's skin, say plastic surgeons

#92

Post by synicalx »

arcticbull wrote: post #63
jordanb wrote: post #15

Earlier quoted context omitted.

I'm sometimes reminded of a parable of an old lady who swallowed a fly...

The problem is she swallowed everything else too. The obesity is a massive problem that needs to be remedied and yes there may be side effects along the way but literally nothing else works for obesity except roux-en-Y gastric bypass. Palid skin is nothing compared to losing your foot to diabetes.

> literally nothing else works for obesity except roux-en-Y gastric bypass

I assume you mean as a therapeutic/last resort treatment?

Re: Ozempic is changing people's skin, say plastic surgeons

#93

Post by Andaith »

arcticbull wrote: post #72

> “Fifteen years ago, I would never have done a lower body lift on a patient unless they had gastric bypass, a lap band, or a gastric sleeve,” he says. Right, because 15 years ago nobody else lost any weight. GLP-1s and roux-en-Y are literally the only two treatments shown in clinical studies that cause people to lose weight and keep it off indefinitely. Maybe the skin is saggy because there’s nothing under it, maybe…

> GLP-1s and roux-en-Y are literally the only two treatments shown in clinical studies that cause people to lose weight and keep it off indefinitely.

Total Diet Replacement (TDP) is apparently also quite effective. This isn't the article I read, but it's talking about the same trial(Direct) so here you go: https://tdmr-europe.com/2024/01/17/experts-demonstrate-total...

Re: Ozempic is changing people's skin, say plastic surgeons

#94

Post by cm2187 »

anakaine wrote: post #43
cm2187 wrote: post #24

Earlier quoted context omitted.

What kind of effort are you talking about? Weight loss has very little to do with exercise and mostly to do with how much you eat. Those drugs allow you to combat the carving when you restrict food. Is fighting the carving the "effort" you think people ought to make?

This, and there's seems to be a number of people with a misconception that getting medical assistance is either cheating, or you're not trying hard enough. As someone who is quite strong and fit, but has a family history of obesity, and who has been packing on the kilos into their 40s - I've recently started with ozempic and it's a breakthrough drug. The incessant never ending demand to eat, that voice which never go…

Yeah, that's the force that makes you go out of the cave to chase a mammoth. Strong force to fight back.

Re: Ozempic is changing people's skin, say plastic surgeons

#96

Post by arcticbull »

synicalx wrote: post #92
arcticbull wrote: post #63

Earlier quoted context omitted.

The problem is she swallowed everything else too. The obesity is a massive problem that needs to be remedied and yes there may be side effects along the way but literally nothing else works for obesity except roux-en-Y gastric bypass. Palid skin is nothing compared to losing your foot to diabetes.

> literally nothing else works for obesity except roux-en-Y gastric bypass I assume you mean as a therapeutic/last resort treatment?

Nothing besides GLP-1s and roux-en-Y has been shown to help people lose a clinically significant (>5%) amount of their body weight and keep it off long term (>5y). Exercise does roughly speaking nothing to help you lose fat (it's great for all sorts of other things), and diet has not been shown to work long-term either due to changes in metabolic rate and hunger leading to ~zero compliance. Most people reverse trajectory around the 6 month mark, and average weight regain after 5 years is 80%.

Re: Ozempic is changing people's skin, say plastic surgeons

#97

Post by taneq »

bamboozled wrote: post #6

It's strange how there is almost never a shortcut to anything. Like a universal law. So now you might get free weight loss without making any effort at all, but you'll also look older in the process? I have to say, my father has been taking it, and I noticed that he does look older all of a sudden...and his weight loss also plateaued. I thought it was just my imagination, but maybe not.

This is basically the ‘no free lunch’ principle, and the thing to keep in mind is that there’s no universal free lunch, but that doesn’t mean no individual lunch is ever free. (The classic example is insulin for diabetics, which most certainly is a win.)

Re: Ozempic is changing people's skin, say plastic surgeons

#98

Post by [deleted] »

Andaith wrote: post #93
arcticbull wrote: post #72

> “Fifteen years ago, I would never have done a lower body lift on a patient unless they had gastric bypass, a lap band, or a gastric sleeve,” he says. Right, because 15 years ago nobody else lost any weight. GLP-1s and roux-en-Y are literally the only two treatments shown in clinical studies that cause people to lose weight and keep it off indefinitely. Maybe the skin is saggy because there’s nothing under it, maybe…

> GLP-1s and roux-en-Y are literally the only two treatments shown in clinical studies that cause people to lose weight and keep it off indefinitely. Total Diet Replacement (TDP) is apparently also quite effective. This isn't the article I read, but it's talking about the same trial(Direct) so here you go: https://tdmr-europe.com/2024/01/17/experts-demonstrate-total...

[deleted]

Re: Ozempic is changing people's skin, say plastic surgeons

#99

Post by cm2187 »

Saline9515 wrote: post #64
cosmicvarion wrote: post #51

Don't these plastic surgeons have a conflict of interest if they perform liposuction? Liposuction is probably wildly more profitable than prescribing a GLP-1 inhibitor.

As the article says, they have patients come anyway to reduce the side effects of GLP-1. Plastic surgeons are like the bank in casino: they always win in the end.

Not the least because aging only goes one way!

Re: Ozempic is changing people's skin, say plastic surgeons

#100

Post by cm2187 »

silverquiet wrote: post #61
JumpCrisscross wrote: post #12

Earlier quoted context omitted.

> strange how there is almost never a shortcut to anything. Like a universal law There are win-win tradeoffs. Vitamins, for instance. If you're running a vitamin deficiency, there isn't a downside to increasing your intake of that vitamin. (Curing acute dehydration via IV is another shortcut that just works.) The Ozempic story, for me, has been more about how we almost seem to be reflexively against the idea of a win…

My perception is that we judge fat people as weak and contemptible and therefore a drug is allowing them to cheat their way out of their sin instead of paying the proper penance (diet and exercise). It's well known that people treat fat people worse; I constantly wonder how aware people are of their own biases? For what it's worth I've been fat before and I've been in shape before. I have my own biases that are beyon…

Ozempic doesn't make you lose weight unless you do a diet. All it does is to make it easy to do a diet by suppressing the craving for food. So it's not like people are losing weight with ozempic while stuffing themselves with burgers.

As for exercise, it has many benefits but is a fairly minor contributor to weight loss. I am doing a bit of a hardcore diet at the moment (helped a ozempic competitor), lost 20kg/44lbs in 3 months, and I noticed no difference in change in weight whether I do 1h of exercise bike daily (max resistance) or whether I do a week without.

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