21–30 of 86 posts
Earlier quoted context omitted.
Slam dunk against EpiPen’s de facto monopoly.
EpiPens have been generic for many years and most people don't buy the brand name EpiPen unless their insurance makes it free. Check CVS and goodrx
My first question is what took so long? For epilepsy, rescue meds to prevent one seizure from triggering another have started coming in the form of nasal spray for at least 5 years already. Before that, outside of hospitals you either had to put a pill under someone’s tongue or cream in their butthole. You couldn’t put it under their tounge during a seizure out of risk they’d bite your finger (I’m currently recoverin…
My bet is that FDA took 5 years longer than reasonable to clear it.
I don't care about the needleless part. The autoinjectors are easy to use and you never see the needle. This is the real win: > The shelf life of neffy is 30 months and allows for temperature exposure up to 122°F (50°C), making it a potentially effective treatment if left in a car or outside for a length of time. If accidentally frozen, neffy can be thawed and administered. [1] The need to keep Epi-Pens below 77 degr…
My first question is what took so long? For epilepsy, rescue meds to prevent one seizure from triggering another have started coming in the form of nasal spray for at least 5 years already. Before that, outside of hospitals you either had to put a pill under someone’s tongue or cream in their butthole. You couldn’t put it under their tounge during a seizure out of risk they’d bite your finger (I’m currently recoverin…
> ARS Pharma will offer neffy at a price of $199 for two doses via digital pharmacy sites like BlinkRx and GoodRx for eligible patients whose insurance plans do not cover neffy. Some commercially insured patients can access the treatment at $25 for each filled prescription of two single-use neffy devices through a co-pay savings program.
I don't care about the needleless part. The autoinjectors are easy to use and you never see the needle. This is the real win: > The shelf life of neffy is 30 months and allows for temperature exposure up to 122°F (50°C), making it a potentially effective treatment if left in a car or outside for a length of time. If accidentally frozen, neffy can be thawed and administered. [1] The need to keep Epi-Pens below 77 degr…
As a practical matter epi-pens work just fine outside spec. Heat just speeds up the degradation. Also see https://www.foodallergy.org/fare-blog/expired-epinephrine-ca... > Forty EpiPen and EpiPen Jr auto-injectors that had been expired for 1 to 50 months were tested. All 40 auto-injectors contained more than 80 percent of the labeled dose
> ARS Pharma will offer neffy at a price of $199 for two doses via digital pharmacy sites like BlinkRx and GoodRx for eligible patients whose insurance plans do not cover neffy. Some commercially insured patients can access the treatment at $25 for each filled prescription of two single-use neffy devices through a co-pay savings program. This is considerably lower than the non-insured cost of an Epi-Pen or generic eq…
I knew someone that was… violently, ridiculously afraid of needles and to have them describe the time they had to stab a roommate with an Epi-Pen — after running outside and failing to find a Good Samaritan to do it — it was like hearing someone describe finding the courage to take a life or something, some kind of war story. He did finally do it, though. He also puked on the person. The guy had some kind of natural…
Earlier quoted context omitted.
EpiPens have been generic for many years and most people don't buy the brand name EpiPen unless their insurance makes it free. Check CVS and goodrx
The ground truth I have from people in my circle is that it is still expensive and challenging to get them. Maybe that is not broadly the case, but based on that ground truth, I want cheap alternatives at scale.
The actual price of 2pk epipen is $109.99 and it lasts many years. As I mentioned in another comment, "Forty EpiPen and EpiPen Jr auto-injectors that had been expired for 1 to 50 months were tested. All 40 auto-injectors contained more than 80 percent of the labeled dose" https://www.foodallergy.org/fare-blog/expired-epinephrine-ca...
Unless some institution forces you to pay more (Eg schools and allergy shot providers checking expiry dates) the actual cost is ~$25/year if you don't have decent insurance and ~$0 if you do
> ARS Pharma will offer neffy at a price of $199 for two doses via digital pharmacy sites like BlinkRx and GoodRx for eligible patients whose insurance plans do not cover neffy. Some commercially insured patients can access the treatment at $25 for each filled prescription of two single-use neffy devices through a co-pay savings program. This is considerably lower than the non-insured cost of an Epi-Pen or generic eq…
The cheapest generic is $110 without insurance at CVS for two doses. https://www.cvs.com/content/epipen-alternative (Sometimes you could need two doses in the event of an emergency, according to doctors.) I know this because I've been buying them for years without use (thankfully), on the off chance my son has a life threatening reaction to eggs.
I think they need some differentiating shape or like assigned danger colors for the most common emergency nasal applications.
Looks just like Narcan. I think some design work needs to go into making sure these are never confused for each other. The result would be likely deadly. I think they need some differentiating shape or like assigned danger colors for the most common emergency nasal applications.