Here's a guy who had epilepsy severe enough that his parents feared to send him to college who made an enormous difference in the lives of many people.
Robin Warren, pathologist who rewrote the science on ulcers, has died
11–20 of 102 posts
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#12Earlier quoted context omitted.
Can help to fix the: "this is caused by stress", when actually you needed antibiotics that already exists and were known at the time :|
Thats a bit of a myth though. Stress is still known to be a factor in causing ulcers. https://www.ingentaconnect.com/content/ben/cpd/2020/00000026...
A perhaps easier to understand explanation of this is this part of a Robert Sapolsky talk on stress, prepositioned to the bit where he talks about the interaction of stress with the bacteria [1]. The summary is that the body is good at repairing the damage the bacteria do, unless the person is under constant stress which inhibits the repair work.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#13I got an ulcer about ten years ago, well after Warren's research, I went to a doctor and he told me that the ulcer was caused by stress. I said something like "didn't someone get a Nobel prize proving that ulcers were bacterial?" and the doctor hadn't heard that and "prescribed" me to get more rest and try and be less concerned about work.
I got a different doctor after that.
Robin Warren is someone who I respected the hell out of. It takes a lot of tenacity and determination to go against something when everyone is constantly telling you you're wrong. He will be missed.
ETA:
I should point out that I am aware that stress can aggravate and (potentially) cause some forms of ulcers, though I really wasn't terribly stressed at that point in my life, which I tried explaining to the doctor and he wouldn't hear it. My job was going fine, I didn't really have any debt, I had a decent relationship with my girlfriend (now wife), I really didn't feel stressed out at all.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#14Another important pathologist who died recently is Dr. Fletcher (he was a president of USCAP at some point)
https://oncodaily.com/stories/115317.html
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#15Earlier quoted context omitted.
Thats a bit of a myth though. Stress is still known to be a factor in causing ulcers. https://www.ingentaconnect.com/content/ben/cpd/2020/00000026...
A perhaps easier to understand explanation of this is this part of a Robert Sapolsky talk on stress, prepositioned to the bit where he talks about the interaction of stress with the bacteria [1]. The summary is that the body is good at repairing the damage the bacteria do, unless the person is under constant stress which inhibits the repair work. [1] https://youtu.be/D9H9qTdserM?si=bLeu9PmUgcCEAT41&t=1759
Stress itself damages the stomach and gut, reducing mucous barrier, as per the Arunabha review.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#16Earlier quoted context omitted.
Can help to fix the: "this is caused by stress", when actually you needed antibiotics that already exists and were known at the time :|
Thats a bit of a myth though. Stress is still known to be a factor in causing ulcers. https://www.ingentaconnect.com/content/ben/cpd/2020/00000026...
I had gastritis (duodenitis, in fact) a couple of years back, and the first thing they did was test me for H. pylori. I didn't have it. Doctor told me a vast majority of people with such issues do.
After a gastroscopy, they concluded that it was just stress and nothing else, but inflamation wouldn't heal on its own, so I got pantoprazole (PPI) and stopped ingesting potentially irritating food (caffeine, alcohol, spicy food). I also shortly changed jobs, which alleviated the stress. Mind you, I never had heartburn, just pain. My condition didn't improve for a while after that, until I stopped drinking carbonated water (the only carbonated beverage I consumed), that fixed it in less than a month. After that, I gradually weaned myself off of pantoprazol in 6 months.
There literally was no other probable cause except for stress (I was stressed, wholly self-induced), and after I switched industries and no longer felt that I'm wasting my time working for peanuts, the PPIs helped cure the symptoms.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#17I got an ulcer about ten years ago, well after Warren's research, I went to a doctor and he told me that the ulcer was caused by stress. I said something like "didn't someone get a Nobel prize proving that ulcers were bacterial?" and the doctor hadn't heard that and "prescribed" me to get more rest and try and be less concerned about work. I got a different doctor after that. Robin Warren is someone who I respected t…
There’s an interesting level to this as there is a link between stress and ulcers. Stress reduces the mucous barrier and how quickly you heal, so reducing stress actually was helping people with ulcers. Antibiotics however where more effective in most but not all cases.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#18I got an ulcer about ten years ago, well after Warren's research, I went to a doctor and he told me that the ulcer was caused by stress. I said something like "didn't someone get a Nobel prize proving that ulcers were bacterial?" and the doctor hadn't heard that and "prescribed" me to get more rest and try and be less concerned about work. I got a different doctor after that. Robin Warren is someone who I respected t…
There’s an interesting level to this as there is a link between stress and ulcers. Stress reduces the mucous barrier and how quickly you heal, so reducing stress actually was helping people with ulcers. Antibiotics however where more effective in most but not all cases.
Yeah I made an edit to kind of clarify on that.
I really wasn't stressed at that time; outside of the typical annoyances of being alive, my life was going pretty ok at that point, which I tried telling the doctor and he didn't believe me. After that I went to a different doc and she gave me antibiotics and I healed after a few weeks.
I am extremely thankful that I have not had an ulcer again since then, because it was the worst thing ever.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#19The vast majority of people still today directly associate any stomach pain with stress as their first thought. I would even venture to say that many doctors still inquire about stress during a consultation. Even though it is not the cause of ulcers, it is true that stress amplifies the symptoms of existing ulcers and increases stomach acid production. Personally, I find stress fascinating.
Re: Robin Warren, pathologist who rewrote the science on ulcers, has died
#20I got an ulcer about ten years ago, well after Warren's research, I went to a doctor and he told me that the ulcer was caused by stress. I said something like "didn't someone get a Nobel prize proving that ulcers were bacterial?" and the doctor hadn't heard that and "prescribed" me to get more rest and try and be less concerned about work. I got a different doctor after that. Robin Warren is someone who I respected t…
The handful of times I've had ulcers in the past it was certainly correlated with stress. Perhaps indirectly through some other effects, but stress feels like part of the equation IME, at least for some people.