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Cure for male pattern baldness given boost by sugar discovery

sheffield.ac.uk

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Re: Cure for male pattern baldness given boost by sugar discovery

#101

Post by viking123 »

formerly_proven wrote: post #42
uh_uh wrote: post #16

Earlier quoted context omitted.

Say more please.

took 1 pill, pp fell off tl;dr While it can have undesirable side effects, these are long-term. But these side effects make it a powerful nocebo for some people to the point where they almost instantly get side effects (nausea, anxiety, sexual dysfunction), despite that being pharmacologically improbable.

It's mostly nocebo, they read about it online for weeks and then try it, and at that point they are so psyched out that they keep watching for every little thing, effectively making it a self fulfilling prophecy.

I started dutasteride when I was 20 and have been on it for many years and it really stops hair loss, because my hair loss was very fast and aggressive.

Re: Cure for male pattern baldness given boost by sugar discovery

#102

Post by AmericanChopper »

seethedeaduu wrote: post #99
AmericanChopper wrote: post #23

Earlier quoted context omitted.

The side effects of finastetide can be pretty nasty, and you might not even notice you have them. You would expect it to suppress your natural testosterone production, which you’re not going to notice unless you ever stop taking it. It can easily reduce your fertility, which again you’re not going to notice unless you’re having trouble conceiving. The reduction in DHT can also have side effects that are far less visi…

DHT is poison

If (adult) DHT was only bad, then you wouldn’t see any adverse side effects from blocking its synthesis. DHT is just an androgen receptor agonist, its effects in adult male biology are not understood very well, including the reasons why DHT blockers (absolutely do) cause a number of adverse side effects.

Re: Cure for male pattern baldness given boost by sugar discovery

#104

Post by TaylorAlexander »

seethedeaduu wrote: post #91
TaylorAlexander wrote: post #74

Earlier quoted context omitted.

If you take a high enough dose of estrogen, generally referred to as estrogen mono therapy, it will knock down your T levels. But high estrogen levels have some risks as well, and different doctors have different preferred approaches. My doctor is willing to do estrogen monotherapy, but I would have to switch from oral pills to injections as the higher dosages taken orally would be hard on the kidneys. Before switchi…

"High" E dosages enough to knock down your T are not that high at all. Also fin won't reduce your T, it might actually increase it, and by using fin instead of duta you still produce dht. Chances are you are still irreversiblly masculinizing if you are on a low dosage of E (including oral). Please consider an actual T blocker, and consider a suitable medication to help with erections.

Im not on a low dose, I take 8mg oral estradiol per day. It’s just not a particularly high dose, just the highest my doctor is comfortable giving someone orally. I don’t care about the testosterone in my system I only want to stop hair loss (I’m very genderfucked non-binary). It was my doctor from the UCSF Transgender Care center that suggested finasteride may have effects similar to that of reducing T (specifically a more estrogen dominant arousal style). I’m already on cialis and previously I’d take 5mg a day normally and 10mg on days where I would have sex, which is a pretty high dose. On finasteride I’ve noticed reduced erection performance even with 15mg cialis which is the most I want to take in a day (20mg is the maximum recommended daily dose).

Also I’m 39, so whatever masculinization I’m due for I suspect has all happened already.

Re: Cure for male pattern baldness given boost by sugar discovery

#105

Post by viking123 »

drumhead wrote: post #47

A cure for baldness is one of those holy grail drugs like a drug to treat obesity, or a drug to de-age your skin. The profit on this is potentially vast and Im assuming the 10 year patent limit wont apply to it.

I guess it's not a full cure but dutasteride is pretty close to one if you start taking it before being like fully bald.

What would the cure be really? Some daily pill that would regrow the hair or just some one time therapy? I don't think it is coming any time soon.

Re: Cure for male pattern baldness given boost by sugar discovery

#106

Post by TheHumanist »

animal531 wrote: post #100

I already have the cure growing in my head. My hairline started receding somewhere in my 30's, but on the one side of my forehead there is this one single remaining hair that refuses to give up, no matter what. The poor guy looks kind of sad out there by himself, but I'm sure if we science him we can discover how to apply his chutzpah to all hair everywhere.

And you let him grow. I started balding around 26 or so and have this tuft in the front that actually doesn't look ridiculous and from.the front makes it look like maybe I'm a little less bald.

I've yet to be able to let that tuft go lol they are trying their damnedest and far be it from me to squash that effort.

Re: Cure for male pattern baldness given boost by sugar discovery

#107

Post by TheHumanist »

worstspotgain wrote: post #72

> Findings from the study show that the deoxy ribose sugar is as effective at regrowing hair as Minoxidil - an existing drug used to treat hair loss Minoxidil is barely effective, especially for something that became widely available. It got approved in the 80s as a topical version of a hypertension drug, and IIRC the McStudy that supported it was funded by the original patent holder. I don't think anyone had much of…

Yeah, that finding unfortunately killed any excitement I may have had for this lol I feel like saying Minoxidip is barely effective is almost even giving it too much credit.

Re: Cure for male pattern baldness given boost by sugar discovery

#108

Post by ImHereToVote »

woolion wrote: post #79

Since this is related to a 'sugar', I wondered if the (keto) diet could have an impact. The metabolic cycles of deoxyribose are mainly related to DNA metabolic pathways, which isn't really related that is the glucose/insulin metabolism. In particular, these DNA pathways are very reliant on nutrient and vitamins (folic acid, B6, B12, ...), , so that is the first thing to take into account in the diet. But further than…

There is a big difference between "sugar" and "a sugar".

Re: Cure for male pattern baldness given boost by sugar discovery

#109

Post by michaelscott »

willcipriano wrote: post #84
michaelscott wrote: post #75

Earlier quoted context omitted.

Completely ancedotal, but I've taken minoxidil and finasteride for a little over a year. I took a break from minoxidil only for a few months and found my hair grew considerably slower than when I was on both. I think this makes sense given what minoxidil is supposed to do, which is not "save the hair" but, as I understand it, accelerate the hair growth cycle

Works fine if you use it prior to going bald. I started in my early 20's and my hair is the same as when I started. It also works on beards.

True, I started as I began thinning and luckily caught it early enough. It hasn't solved the pre-existing thinning completely, but it's prevented any further loss and resurrected enough follicles that were on the verge of death that if you were to look at me on the street, you wouldn't say I'm thinning/balding.

The problem with doing anything after "full" balding has progressed is that the follicles have just completely died off, which is way more difficult to solve than preserving or stimulating existing growth

Re: Cure for male pattern baldness given boost by sugar discovery

#110

Post by andyroid »

aikinai wrote: post #96
canucker2016 wrote: post #83

Earlier quoted context omitted.

I remember a female comedian, (perhaps Amy Schumer), joking that when she saw Jeff Bezos, she knew there was no cure for baldness. If a multi-centi-billionaire is bald, then there's no viable baldness cure at any price.

It’s a funny joke, but debunked by Elon Musk, along with a lot of other celebrities and normal people.

Does a hair transplant really count as a cure though? It’s more akin to a pricey baseball cap.
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