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Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

nature.com

171–180 of 236 posts

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#171

Earlier quoted context omitted.

Brains find familiar things comforting and "good". Brains can also find brand new things, especially experiences that have nothing in common with anything we've encountered in the past, as "bad". This applies to almost everything. Music is a good example, someone who has only grown up listening to folk music will likely find death metal incredibly hard to listen to, but they may find folk metal a little bit relatable…

As it pertains to food and drink I don’t agree with or understand repeatedly trying something I don’t like. It’s good that you find that it works for you but it doesn’t for me. Cabbage makes me vomit. I don’t like it and will never again knowingly try it. Once was enough.

> As it pertains to food and drink I don’t agree with or understand repeatedly trying something I don’t like

Let me give an example.

My wife used to hate lamb. An American style lamb roast[1] was atrocious to her.

Then one day at a friends house we had super thin cut highly seasoned grilled cumin lamb. It is a completely different taste than a lamb roast. She liked it.

So after a few times of having that dish, that she was open to trying some other lamb dishes, but always highly seasoned and cut into small chunks. These other dishes she did not like before, but now she found that she did.

Her brain had adopted the idea that "small pieces of highly seasoned lamb taste good".

> I don’t like it and will never again knowingly try it.

There is plenty of horrible cabbage out there. Like, awful stuff that I would not want to eat.

But a Korean kimchi cabbage is a lot different than a Vietnamese pickled cabbage which is a lot different than sauerkraut which is a lot different that cabbage fried in bacon fat.

Seriously if you are a person who likes bacon, try some thin sliced cabbage fried in bacon fat. I know people who hate sauerkraut, but who love crispy fried cabbage.

It also depends on the type of cabbage, and there are lots of types. Different types of cabbage are as different as grapefruits are to oranges, if someone hates grapefruit they should still give oranges a try. And if someone hates lemon juice they should still try orange popsicles! (and maybe that person hates all citrus fruits equally, but they won't know until they try more than 1!)

But I also have food that I just cannot eat w/o puking it right back out. Mushrooms are my weakness, but only certain types of mushrooms. Pretty much every type of mushroom used in western cuisine makes me sick, but I am fine eating enoki mushrooms or wood ear mushrooms, and I'm glad I gave both a try despite my vomiting reaction to button/portobello mushrooms!

[1] TBF American style lamb roasts are a waste of a perfectly good lamb.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#172

Earlier quoted context omitted.

With all due respect, I wouldn't commit any crimes if caffeine was suddenly illegal. I'd have headaches for a few days and that'd be it.

With all due respect, I've heard the exact same thing from a number of folks taking Opioids after surgery. They were right, fortunately, and navigated their withdrawal symptoms without incident. I'm sure you're right too, but it's not a particularly convincing argument. I've definitely seen behaviors that horrify me from some of the caffeine addicts in my life. I bet caffeine prohibition would lead to a rise in domes…

A Starbucks speakeasy sounds awesome actually.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#173
post #143

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> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

I agree with you about the experience, but nobody who really likes coffee goes to Starbuck for the taste:-). They are really addicted

we used to take a 10m walk to a SB just to gtfo the office, to have a walk after the hour+ commute, to people watch, and to BS with the coworkers. it just also happened to be a great source of hot sugar that went well with the baileys. addiction to having a mental break from the stresses, yes, but in no way addicted to the caffine (nor sugar)

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#174
post #17

Recently I've learned that half of the people are slow caffein metabolizers. The caffein stays longer in their system and it might negatively affect their sleep. Considering how many people drink coffee, I think a lot of people are affected by this.

Found that out the hard way twenty years ago. The stated half life is NOT for me what they say.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#175
post #143

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

I agree with you about the experience, but nobody who really likes coffee goes to Starbuck for the taste:-). They are really addicted

It might be true that they're addicted to caffeine, but it's likely also true that they're addicted to Starbucks

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#176
post #30

I love my caffeine. But caffeine is an addictive, highly profitable substance. So advertising it and trying to promote it as somehow having real health benefits is widespread. I would not be surprised if routine consumption of caffeine was at least mildly detrimental to health. I think some drugs have managed to gain a special place in our society . Advertising and lobbying warps our perception of these drugs. I even…

> highly profitable substance Yes and no. I've been a fan of caffeine pills for years. They are very cheap, readily available (portable), and most importantly to me offer completely consistent dosing. With caffeine pills I'm able to ensure I stay below the FDA recommended maximum daily intake of 400 mg (worst case). Another fun bonus - when a physician asks you what your caffeine intake is and you respond in milligra…

You’re missing out on the phytochemicals that contribute to the positive effects of drinking tea or coffee. You’re getting all the bad (and good) of chronic caffeine stimulation, with none of the plant medicine benefits that tea and coffee drinkers receive.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#177
post #144
post #79

Earlier quoted context omitted.

My wife uses caffeine pills on occasion but I prefer energy drinks most mornings alongside something like toast. Obviously more expensive but the drink has a slower come-up (likely due to the extra water and food). Whenever I do take pills instead, I'm in a rush so I'm not drinking more water than necessary and definitely not eating anything. I like the Celsius drink mixes since I can put one in my water bottle and d…

> I like the Celsius drink mixes since I can put one in my water bottle and dose slowly over the course of the morning but they aren't that much cheaper than buying a case of cans. In addition to your caffeine, you get a “healthy” dose of synthetic sugar (aka Sucralose) [1] and other crap added by the drink company to market it as “healthy” Personally, I can’t stand those drinks. Every “0 calorie, 0 sugar” drink is n…

[deleted]

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#178

Earlier quoted context omitted.

> highly profitable substance Yes and no. I've been a fan of caffeine pills for years. They are very cheap, readily available (portable), and most importantly to me offer completely consistent dosing. With caffeine pills I'm able to ensure I stay below the FDA recommended maximum daily intake of 400 mg (worst case). Another fun bonus - when a physician asks you what your caffeine intake is and you respond in milligra…

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

I think true coffee lovers like decaf (lets them drink more coffee)

hard to get good decaf though, it seems to me like trying to buy diet donuts.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#179
post #35

Earlier quoted context omitted.

I would claim that for regular users of caffeine, it merely restores function to a baseline level.

Everybody is different. 3 years ago I took a summer and then autumn off of caffeine; my intent was to quit and only use caffeine in "times of need". This would be an on-brand thing for me to do as a person, and something I wanted pretty bad. But after 4 full months without touching any caffeine, my mood/energy levels never returned or even really rebounded any further than they did after the first month. I'm just a d…

Possessing the GG variant of COMT rs4680 gene might explain this. Conversely, AA types might get overstimulated and irritable.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#180
post #30

I love my caffeine. But caffeine is an addictive, highly profitable substance. So advertising it and trying to promote it as somehow having real health benefits is widespread. I would not be surprised if routine consumption of caffeine was at least mildly detrimental to health. I think some drugs have managed to gain a special place in our society . Advertising and lobbying warps our perception of these drugs. I even…

Alcohol reduces functions, caffeine clearly enhances functions. If caffeine was involved in nearly all violent crime like alcohol is, we would think differently of it.

I think it is a matter of perception.

For example, lots of DUI type accidents are blamed on alcohol, but it might actually be sleep deprivation that is the most fundamental cause of the accident.

In a similar way, I wonder if similar sleep-related accidents or incidents could more properly have caffeine as a root cause (after it has worn off)

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