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Anti-ageing 'supermodel granny' drug extends life in mice by 25%

bbc.com

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Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#3

Ah yes, the never ending reign of the boomers would be great. just great. Though in seriousness, pretty amazing if this works in humans. Peptide therapy seems huge lately.

An antibody is not a peptide [1]. This drug is an antibody that targets the protein interleukin-11.

Peptides are very short amino acid sequences.

1. https://www.sciencedirect.com/science/article/abs/pii/S13601...

Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#5
As an anti-aging intervention, this is useless because it still doesn't uncover the master organism development regulator, and it doesn't actually "fix" aging, it doesn't make the organism believe that it's younger. The aging process still happens and the organism still dies of the passage of time.

It might be useful as a lead to that master regulator, though. Or it might be not.

Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#6
post #5

As an anti-aging intervention, this is useless because it still doesn't uncover the master organism development regulator, and it doesn't actually "fix" aging, it doesn't make the organism believe that it's younger. The aging process still happens and the organism still dies of the passage of time . It might be useful as a lead to that master regulator, though. Or it might be not.

I’d still take it (or, something that does the same but is proven safe and effective in humans) while waiting for something that matches your desiderata. I’ve seen what ageing can do to people,…

Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#7
post #6
post #5

As an anti-aging intervention, this is useless because it still doesn't uncover the master organism development regulator, and it doesn't actually "fix" aging, it doesn't make the organism believe that it's younger. The aging process still happens and the organism still dies of the passage of time . It might be useful as a lead to that master regulator, though. Or it might be not.

I’d still take it (or, something that does the same but is proven safe and effective in humans) while waiting for something that matches your desiderata. I’ve seen what ageing can do to people,…

All you need is something that extends your healthspan at slightly greater than the rate that new discoveries to extend your healthspan are made.

Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#9
post #7
post #6

Earlier quoted context omitted.

I’d still take it (or, something that does the same but is proven safe and effective in humans) while waiting for something that matches your desiderata. I’ve seen what ageing can do to people,…

All you need is something that extends your healthspan at slightly greater than the rate that new discoveries to extend your healthspan are made.

Yes, this is called longevity escape velocity, except this is not quite how aging works. The organism wants to destroy itself. It's part of the developmental program that starts with conception but eventually turns self-destructive. Trying to use the modern medical approach, where the body is assisted with what it wants to do anyway, is going to be an uphill battle.

Re: Anti-ageing 'supermodel granny' drug extends life in mice by 25%

#10
post #5

As an anti-aging intervention, this is useless because it still doesn't uncover the master organism development regulator, and it doesn't actually "fix" aging, it doesn't make the organism believe that it's younger. The aging process still happens and the organism still dies of the passage of time . It might be useful as a lead to that master regulator, though. Or it might be not.

Fifteen to twenty extra years of lifespan is useless? With reduced odds of cancer?

(20-25% longer life x 80 year current lifespan.)

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