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Research into homeopathy: data falsification, fabrication and manipulation

skeptic.org.uk

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Re: Research into homeopathy: data falsification, fabrication and manipulation

#62

Homeopathy is BS, but understanding of edible foraging and plant chemistry is surprisingly helpful for better health and diet. As an example onions and garlic do nothing to cure or address asthma. They do contain an active chemical that vaporized when they are cut which causes uncontrolled tear production. That same chemical agitates the throat in a way that arrests some amount of night coughing induced by asthma. An…

> Another is that common fruits like pears, apples, and citrus contain drug like chemicals that alter the metabolism. This is super potent in grapefruit and has been known to cause fatal drug interactions in people on prescribed medicine. Grapefruit does not "alter the metabolism." Furanocoumarin binds to a receptor in the gut which causes some medications to pass through the gut much faster than normal which affects…

Grapefruit contains compounds that inhibit Cytochrome P450 and this will affect how various drugs will be metabolized. That is a very direct effect on metabolism and will affect a variety of drugs, but certainly not all of them.

Re: Research into homeopathy: data falsification, fabrication and manipulation

#63

I still don't understand why these can be sold in American pharmacies.

It's considered a dietary supplement, which is governed by the dietary supplement health enforcement act, which in turn classifies dietary supplements as a food product.

Very much false.

1. Under the Federal Food, Drug, and Cosmetic Act, homeopathic products are subject to the same requirements related to approval, adulteration and misbranding as other drug products. https://www.fda.gov/drugs/information-drug-class/homeopathic...

2. Homeopathic products are "classified as either over-the-counter (OTC) or prescription medicines." https://www.chpa.org/about-consumer-healthcare/faqs/faqs-abo...

Re: Research into homeopathy: data falsification, fabrication and manipulation

#64

Homeopathy is BS, but understanding of edible foraging and plant chemistry is surprisingly helpful for better health and diet. As an example onions and garlic do nothing to cure or address asthma. They do contain an active chemical that vaporized when they are cut which causes uncontrolled tear production. That same chemical agitates the throat in a way that arrests some amount of night coughing induced by asthma. An…

> Another is that common fruits like pears, apples, and citrus contain drug like chemicals that alter the metabolism. This is super potent in grapefruit and has been known to cause fatal drug interactions in people on prescribed medicine. Grapefruit does not "alter the metabolism." Furanocoumarin binds to a receptor in the gut which causes some medications to pass through the gut much faster than normal which affects…

That's not the only mechanism (see other response also).

https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_intera...

Re: Research into homeopathy: data falsification, fabrication and manipulation

#66

I had horrible pollen allergies. My mother took me to a homeopath (in addition to regular doctors) She prescribed some tablets / pills to dissolve under the tunge, that had some pollen in them. It worked pretty well for allergies but not the best for teeth. Just building up resistance I would think. I know you can get similar treatment now from regular doctors. So my one and only interaction was fairly successful. I…

> I had horrible pollen allergies. My mother took me to a homeopath (in addition to regular doctors) She prescribed some tablets / pills to dissolve under the tunge, that had some pollen in them.

You don't know that it worked. This is an example of the regression fallacy.[1] This is why we have controlled trials.

1. https://en.wikipedia.org/wiki/Regression_fallacy

Re: Research into homeopathy: data falsification, fabrication and manipulation

#67

I still don't understand why these can be sold in American pharmacies.

In France they were funded by the social security up to 15%, but luckily this stopped in 2021. I had some as a kid and my mom is still a strong "believer" in them. I don't see any harm in selling them IF and only if they don't prevent people from taking other "real" treatments. But other than this it's just placebo.

Re: Research into homeopathy: data falsification, fabrication and manipulation

#68
post #56

I still don't understand why these can be sold in American pharmacies.

THE PLACEBO EFFECT: It works even when you know it's a placebo.

This is an incorrect summary of the placebo effect. The placebo effect does require the patient to either believe it is effective, or at least not knowing clearly it is ineffective.

This is why clinical studies don't tell neither group (neither the treated group nor the control group) who is in which group, to not spoil the results.

And also, this is why homeopathy puts so much effort into spreading the belief they are effective despite all odds, up to the point of trying to convince people to abandon basic scientific principles.

Re: Research into homeopathy: data falsification, fabrication and manipulation

#69
post #60

I still don't understand why these can be sold in American pharmacies.

They are powerful placebos, so the believers have become permanently duped.

Placebos work even if users know it's a placebo. I don't for a second believe in any of homeopathy claims, but I still buy and use it, because placebo works. Especially so when price and all other medicine-looking rituals around it are maintained.

Re: Research into homeopathy: data falsification, fabrication and manipulation

#70

Homeopathy is BS, but understanding of edible foraging and plant chemistry is surprisingly helpful for better health and diet. As an example onions and garlic do nothing to cure or address asthma. They do contain an active chemical that vaporized when they are cut which causes uncontrolled tear production. That same chemical agitates the throat in a way that arrests some amount of night coughing induced by asthma. An…

> Another is that common fruits like pears, apples, and citrus contain drug like chemicals that alter the metabolism. This is super potent in grapefruit and has been known to cause fatal drug interactions in people on prescribed medicine. Grapefruit does not "alter the metabolism." Furanocoumarin binds to a receptor in the gut which causes some medications to pass through the gut much faster than normal which affects…

> Grapefruit does not "alter the metabolism."

Wrong. https://en.wikipedia.org/wiki/Cytochrome_P450

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