Live data from Hacker News

Creatine improves physical function and body composition in older adults

pubmed.ncbi.nlm.nih.gov

41–50 of 98 posts

Re: Creatine improves physical function and body composition in older adults

#41
post #17
post #10

Earlier quoted context omitted.

Years ago I started lifting weights quite a bit. And my hairline started receeding sort of in the corners of my forehead. Stopped lifting and it stopped. I suspect the testosterone boost from strength training.

Curious, why does higher T cause hair loss if T is naturally higher in adolescence where there is less hair loss.

For one, it's also about the hair follicle's sensitivity to circulating androgens. Maybe that changes with age.

Re: Creatine improves physical function and body composition in older adults

#42
post #27
post #17

Earlier quoted context omitted.

Curious, why does higher T cause hair loss if T is naturally higher in adolescence where there is less hair loss.

Testosterone gets converted into DHT, and DHT causes male pattern baldness. Maybe younger males don't convert as much testosterone into DHT as older guys do

DHT also stimulates beard growth, so at least you get a return on investment.

Re: Creatine improves physical function and body composition in older adults

#43
post #32

I've worked out my whole life (since around age 14, now over 35) and had periods where I did a lot of supplements like creatine or pre-workout. I no longer bother with them, although creatine is one of the more well researched / "real" supplements, so you're better off with that than lots of others. To me though they've never really done anything (besides cost money). In my opinion the best bang for your buck is drin…

If we’re sharing anecdata, Creatine has very noticeable positive impact on recovery time for me. Without it, I basically have to take an extra rest day between workouts.

Re: Creatine improves physical function and body composition in older adults

#44

I have creatine on my short list of supplements to try this summer. Anything you wished you knew when starting it? Do I need to worry about buying a specific brand known for being “clean”?

This is likely a complete coincidence, so take my experience with a grain of salt. However… I am somewhat convinced that creatine caused me to develop appendicitis last summer about 5 days into a supplementation cycle. My best guess is that increased fluid retention (caused by creatine) caused vascular congestion at the verniform appendix.

On the (monkey’s paw) plus side, the perioperative IV fluids plumped up my muscles and gave a muscle man appearance that I was after for several days. I believe I was up 10-15 lbs in water weight when I came home.

Re: Creatine improves physical function and body composition in older adults

#45
post #22

Earlier quoted context omitted.

I think you can add supps that lower T to DHT conversion. I have just started on this journey.

Taking creatine, RU58841 or CB0301 are even better than supplements.

> RU58841 or CB0301

Are these commercially available for topical use on the head?

> better than supplements

Supplements don't strongly target specific issues, but they work across the board to weakly target dozens of issues, including issues that one doesn't even known one has. As such, it often takes a lot of supplements together to begin to strongly target an issue.

Re: Creatine improves physical function and body composition in older adults

#46
post #32

I've worked out my whole life (since around age 14, now over 35) and had periods where I did a lot of supplements like creatine or pre-workout. I no longer bother with them, although creatine is one of the more well researched / "real" supplements, so you're better off with that than lots of others. To me though they've never really done anything (besides cost money). In my opinion the best bang for your buck is drin…

I know caffeine is detrimental to my workouts because it dehydrates me and raises my heart rate. I have clear personal data on this. Creatine is well established as a substance that has a real measurable positive impact on people.

Re: Creatine improves physical function and body composition in older adults

#47

Earlier quoted context omitted.

I assume you're aware of the water weight gain. Otherwise, it's effects are fairly modest.

I don't know the first thing about these authors or if this paper was funded by a supplement company... but apparently that is a myth[1]? You may gain some water weight for a week or two, but that seems to stop. [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871530/

You gain a few pounds of water weight during the "loading" phase (the entire idea is that it's drawing water and metabolic fuel into the muscles) and then it plateaus as long as you keep taking it. When you stop taking it, the water weight will come off.

I workout seriously enough that people notice if that means anything, and I take creatine. It's one of those things with the most proven upsides and essentially no downsides. That said, the effects are nothing like serious PEDs - not that I can personally compare those things, but it's quite clear that gear is a whole other level.

Re: Creatine improves physical function and body composition in older adults

#48

I have creatine on my short list of supplements to try this summer. Anything you wished you knew when starting it? Do I need to worry about buying a specific brand known for being “clean”?

Creatine and caffeine possibly have a negative interaction - search PubMed for papers - eg

https://pubmed.ncbi.nlm.nih.gov/26219105/

I’m very slow and stiff in the mornings and I drink a lot of black coffee to mitigate that.

Then, late afternoon, perhaps 6 to hours later, I take my creatine monohydrate for the day just before my ocean swim.

Re: Creatine improves physical function and body composition in older adults

#49
post #32

I've worked out my whole life (since around age 14, now over 35) and had periods where I did a lot of supplements like creatine or pre-workout. I no longer bother with them, although creatine is one of the more well researched / "real" supplements, so you're better off with that than lots of others. To me though they've never really done anything (besides cost money). In my opinion the best bang for your buck is drin…

I know caffeine is detrimental to my workouts because it dehydrates me and raises my heart rate. I have clear personal data on this. Creatine is well established as a substance that has a real measurable positive impact on people.

It depends on your goals and heart health. If you want to burn through fat fast, then caffeine before heavy cardio workouts is the way to go (assuming your heart is in good condition)

Re: Creatine improves physical function and body composition in older adults

#50
post #40
post #32

I've worked out my whole life (since around age 14, now over 35) and had periods where I did a lot of supplements like creatine or pre-workout. I no longer bother with them, although creatine is one of the more well researched / "real" supplements, so you're better off with that than lots of others. To me though they've never really done anything (besides cost money). In my opinion the best bang for your buck is drin…

Keep in mind every body is different, and responds differently to inputs. Creatine may not have done much for your body, but that absolutely does not mean it won't be very beneficial for others. FWIW, coffee destroys me - I get the sweats, by heartbeat goes jittery and later in the day I crash HARD. It makes my stomach churn and grumble too. So for me, coffee is terrible advice.

Try tea instead of coffee, sounds like you're just taking too much caffeine
Post reply on HN