Start with the customer needs rather than the technology. Do you have some specific product ideas? Those ideas would help steer technology decisions, particularly during the initial prototyping phase.
When you've got the problem you want to work on, is a PWA the best method of use/distribution/discovery?
Perhaps a mobile app is the best method, or a hardware device.
When you're thinking about what you want to build, don't forget about distribution. There is a saying that 1st time founders focus on product, 2nd time founders focus on distribution.