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Viagra improves brain blood flow and could help to prevent dementia

ox.ac.uk

201–210 of 289 posts

Re: Viagra improves brain blood flow and could help to prevent dementia

#201
post #33

Earlier quoted context omitted.

Viagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.

>Viagra doesn't "make" you hard, you still need sexual stimulus. That's Cialis, Viagra should make you hard even when you're in the confession booth talking to a priest.

which one makes the priest hard?

Re: Viagra improves brain blood flow and could help to prevent dementia

#202

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

> Who knows what to believe. This may be a sincere statement, but I'm not sure it's a helpful one. What data do we have? A 2:1 advantage in published studies that it does help. Since there is no such thing in science as absolute proof of anything, these are pretty good odds. Certainly more work will be done in the future to try to replicate the results and figure out the one negative outcome. But until then, we canno…

Studies aren't conducted at random, it's not really valid to sample them as though they were. Major selection bias.

Re: Viagra improves brain blood flow and could help to prevent dementia

#203

Earlier quoted context omitted.

Does it need to be, though? You can survey healthy but senior populations about their habits, and then over the following years track what happens. If medical records were public, the answers could even be in those for any medicines that are prescription based. You could then make statements like "A% of patients who took drug B within C years did/didn't develop disease D".

That's not a randomized controlled trial though. You might find a correlation, but you couldn't actually establish causation, or eliminate hidden variables.

We have to get over this false meme where people think RCTs prove causation and the rest prove correlation.

An RCT doesn’t prove causation, it only might observe another correlation that contributes to our causal inferences based on the convergence of evidence.

We don’t have RCTs for most things that you take for granted.

Re: Viagra improves brain blood flow and could help to prevent dementia

#205

Earlier quoted context omitted.

It is prescribed for benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating—not just for ED

If you want to pretend to be old, Strattera gives you the effects of this as a side effect.

Another weird effect was that my ejaculation and orgasm were seconds apart. Don’t remember which came first (pun). Hated that drug.

Re: Viagra improves brain blood flow and could help to prevent dementia

#206

Earlier quoted context omitted.

Not OP, but their statement read as if that effect wears off after the body develops tolerance to the medication. So, yes they did for a while (it was annoying) but no they don't now (for a few months)

There is NO tolerance development, on the contrary, increasing vascular health by long term PDE5 treatment and increasing psychological confidence over time make the treatment more effective with time. https://www.sciencedirect.com/science/article/pii/S205011611...

The first time I took sildenafil I had a bad headache and nausea, the next couple of times I didn't suffer from nausea and the headache wasn't as severe. I don't suffer from any side effects now other than my nose getting a bit stuffy every now and then, so in that sense I developed a tolerance to the medication's side effects. The boner effects still work just as reliably as day one, no tolerance development for me there.

Re: Viagra improves brain blood flow and could help to prevent dementia

#207
post #33

Earlier quoted context omitted.

Viagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.

>Viagra doesn't "make" you hard, you still need sexual stimulus. That's Cialis, Viagra should make you hard even when you're in the confession booth talking to a priest.

I have experience with both, this is not the case.

Re: Viagra improves brain blood flow and could help to prevent dementia

#208

Earlier quoted context omitted.

Not OP, but their statement read as if that effect wears off after the body develops tolerance to the medication. So, yes they did for a while (it was annoying) but no they don't now (for a few months)

Or they grew accustomed to the erections and no longer found them annoying, which is how I read it.

or other people found them annoying

Re: Viagra improves brain blood flow and could help to prevent dementia

#209

Earlier quoted context omitted.

>Viagra doesn't "make" you hard, you still need sexual stimulus. That's Cialis, Viagra should make you hard even when you're in the confession booth talking to a priest.

which one makes the priest hard?

Viagra was approved in the 90’s and Cialis in 2003, so I’m guessing none of them..

Re: Viagra improves brain blood flow and could help to prevent dementia

#210

All you need is regular exercise to improve blood flow

> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. I mean, I think if going for a walk were a magic bullet for stroke rehabilitation, someone would have noticed by now.

I'm not knowledgeable about stroke rehabilitation specifically, but the benefits of walking are extremely robust. Especially if you're talking about the difference between a totally sedentary lifestyle and one which includes a substantial amount of walking.
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