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Viagra improves brain blood flow and could help to prevent dementia

ox.ac.uk

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Re: Viagra improves brain blood flow and could help to prevent dementia

#111

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

Maybe they forgot what they said before?

Re: Viagra improves brain blood flow and could help to prevent dementia

#112
post #4

Earlier quoted context omitted.

You take it for this purpose or why?

It is prescribed for benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating—not just for ED

There are many off label uses. Pulmonary Hypertension for one.

Re: Viagra improves brain blood flow and could help to prevent dementia

#113
post #108

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

Could be different for different folks

Different strokes for different folks?

Re: Viagra improves brain blood flow and could help to prevent dementia

#114

Well. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is no…

Viagra is prn, you should not take it 3x/day. Cialis is a daily dose.

Re: Viagra improves brain blood flow and could help to prevent dementia

#115

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

> Who knows what to believe. This may be a sincere statement, but I'm not sure it's a helpful one. What data do we have? A 2:1 advantage in published studies that it does help. Since there is no such thing in science as absolute proof of anything, these are pretty good odds. Certainly more work will be done in the future to try to replicate the results and figure out the one negative outcome. But until then, we canno…

Might be a 2:1 but we also have to take into account the level of evidence each study provides.

Re: Viagra improves brain blood flow and could help to prevent dementia

#116

Well. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is no…

Viagra is prn, you should not take it 3x/day. Cialis is a daily dose.

I was talking about the regime used in the study. If you read the article you'll find that

Re: Viagra improves brain blood flow and could help to prevent dementia

#117
post #33
post #26

> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. Each participant received sildenafil, a placebo, and cilostazol (a similar drug) over three-week periods in a randomised order. I feel like dudes will know if they got Viagra or not? It doesn't seem like cilostazol…

Viagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.

> Viagra doesn't "make" you hard

It definitely does.

> you still need sexual stimulus.

Not really, or to a much lesser extent.

Re: Viagra improves brain blood flow and could help to prevent dementia

#119

I always wonder if there is a circular logic flaw in survey studies of recreation and dementia: could it be that the folks who are chasing Viagra or running marathons don't get dementia, because the ones with dementia don't pursue these activities?

This is known as a confounding bias. A quality study should try to eliminate the obvious ones, but of course there may still he an infinite number of hidden confounding variables.

Re: Viagra improves brain blood flow and could help to prevent dementia

#120
post #3

It needs prescription, correct?

In the US, yeah, but arguably it shouldn't be. Probably the only good reason for controlling it is risk of priapism from people using it stupidly, which is an extremely bad "go to the ER now" condition.
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