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Viagra improves brain blood flow and could help to prevent dementia

ox.ac.uk

61–70 of 289 posts

Re: Viagra improves brain blood flow and could help to prevent dementia

#61
you know what else would?

walkable cities

more time off from work

more third spaces

less air pollution

less inequality

of course none of that "increases productivity or GDP" so the ruling class won't consider it. of course when they start dying like Japan with low birth rates, their 'solution' is to have a government funded dating app instead of doing the obvious.

Re: Viagra improves brain blood flow and could help to prevent dementia

#62

50mg 3x a day, according to the study: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.124.32432... Seems high to me, but I've never taken the drug. I assume most people take it just a few times a week for it's intended use? Is anyone aware of research that shows positive benefits to health at recreational doses?

That’s a standard dose. 3X per day is because it has a short half life.

> Is anyone aware of research that shows positive benefits to health at recreational doses?

Recreational doses? What does that mean? Excessive vasodilation isn’t going to be fun. You actually need some vasoconstriction to balance your blood pressure. Too much and you’re just going to get headaches and lightheaded. Excessive vasodilation would be expected to worsen cognition.

Re: Viagra improves brain blood flow and could help to prevent dementia

#63
post #4

Earlier quoted context omitted.

You take it for this purpose or why?

It is prescribed for benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating—not just for ED

I take it on doctor’s orders to recover from prostate cancer. Improving the circulation in that area should help rebuilding tissue.

Re: Viagra improves brain blood flow and could help to prevent dementia

#64
post #31

All you need is regular exercise to improve blood flow

Simple solutions to hard problems seem to be falling out of favor.

Actually, exercise lowers cGMP (and low cGMP is what Viagra reverses) so your "simple solution" is actually totally wrong.

Re: Viagra improves brain blood flow and could help to prevent dementia

#66

you know what else would? walkable cities more time off from work more third spaces less air pollution less inequality of course none of that "increases productivity or GDP" so the ruling class won't consider it. of course when they start dying like Japan with low birth rates, their 'solution' is to have a government funded dating app instead of doing the obvious.

Less air pollution does increase productivity (air pollution is actually really bad for your mental performance, it's a surprisingly strong effect) and it seems to me "the ruling class" does consider it seeing as the Clean Air Act exists.

Btw, Japan has walkable cities of course but also has low inequality (but not so high wealth). Approximately nothing is known to increase birth rates except for being highly religious though; it seems they mostly collapse when people have anything else to do for fun besides have sex. So basically it's caused by being on your phone too much.

Re: Viagra improves brain blood flow and could help to prevent dementia

#67
post #32

Saunas, hot baths, and excercise improve blood flow.

This is America: we demand a low-effort, overpriced solution, preferably in pill form.

Not everyone on HN is from the US, and the study in question is from the UK...

Re: Viagra improves brain blood flow and could help to prevent dementia

#68

Viagra increases the effect of nitric oxide, which is bad stuff when it gets into cytochrome complex iv in the mitochondria (IIRC). I would personally suspect based on that, that its effects on brain health would be negative in spite of blood flow.

Nitric oxide bad for you? Pretty sure it is good for you ,otherwise super foods like beets and leafy greens would be bad for you.

Leafy greens can be bad if you're sensitive to oxalates. Depends how you cook them though.
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