Same old scientific research like I've been doing for over 40 years.
Back then if you wanted to do something where you actually "needed money" you might as well give up right away.
I guess it's a little bit like it is now that inflation has pushed anything like that out of reach for so many people who were closing in on leveraging those type abilities just a few years ago. Fortunately it's not as bad yet as it was in the 1970's.
There was no other option but to get more progress accomplished using less resources.
Especially monetary resources, this can be some of the hardest to come by, even well-heeled people can just sometimes be so greedy.
One cost that was skyrocketing so badly was energy, and it doesn't even move the needle if you can't get your consumption down to about 10% of what average consumers use. It's not easy and it takes years living within your means, working within your means, even when you do not have the cash flow of an average consumer, you can end up quite early not feeling at all like you need more money to make maximum progress compared to some very well-financed operations.
Of course some money is essential but it's good over the long term not to have an ongoing perceived feeling of shortage over what you don't have, that can be the more limiting factor.
I would say questions like this "Ask HN" are something that comes up often for more mainstream technical operators. So many are mainly working for a paycheck and money is always on their mind.
It's been so many decades and times of less-than-average money have not been a limitation on my rate of progress, operating within my means.
At the other end of the spectrum, for those who might be interested in energy projects that people would love, no matter how much money you have, I've got something you can't afford ;)