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New gel breaks down alcohol in the body

ethz.ch

191–200 of 263 posts

Re: New gel breaks down alcohol in the body

#192

Earlier quoted context omitted.

what for? sugar is already broken down in your body into glucose to be absorbed. there are already enzymes you can take to help break it down faster, but it's all going to be absorbed regardless. perhaps what you really want is something to block glucose absorption?

You could invent resistant bacteria that eats all the sugar in your stomach. There are already such but they are lethal if you don't do much about them, but maybe it is possible to make nice versions of them that just eats sugar and don't kill you by eating everything.

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Re: New gel breaks down alcohol in the body

#193
post #79
post #44

Earlier quoted context omitted.

Dihydromyricetin[1] can accomplish this remarkably effectively. It's available on Amazon. Also works great for hangovers. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292407/

Just a warning to everyone: This effect doesn't seem to have much scientific support beyond the cited paper. Other work has followed up and was not able to replicate: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603706/ .

The test is trivial - take a breathalyzer and compare results after say 2, 3, 5 beers before and after. Some mental / IQ test could be added to make sure we don't have folks driving around passing breath test while being very drunk.

Something tells me if they can't provide such a trivial result, it ain't working as folks expect (and god knows what nasty side effects it can have).

Re: New gel breaks down alcohol in the body

#194
post #123

Earlier quoted context omitted.

> Self-control is like a muscle: exercise it frequently, and it gets stronger. It also gets tired and needs rest, and it atrophies with disuse. Addiction is not a matter of self-control.

It's 100% a matter of self-control.

Whatever addiction, you’ll only get past it by assuming and believing it is under your control, paradoxically. Playing victim is, as very often in life, the opposite of empowering.

Re: New gel breaks down alcohol in the body

#195

Earlier quoted context omitted.

what for? sugar is already broken down in your body into glucose to be absorbed. there are already enzymes you can take to help break it down faster, but it's all going to be absorbed regardless. perhaps what you really want is something to block glucose absorption?

You could invent resistant bacteria that eats all the sugar in your stomach. There are already such but they are lethal if you don't do much about them, but maybe it is possible to make nice versions of them that just eats sugar and don't kill you by eating everything.

Ehm, we humans need a certain amount of blood sugar to survive. Having such a resistant bacteria living in my stomach seems a terrible idea ..

Re: New gel breaks down alcohol in the body

#196

Earlier quoted context omitted.

Sounds like maybe the "alcohol free"/"0.0%" beer (not really 100% alcohol free) is something you should try. Tastes and looks like beer, but doesn't come with the buzz (which is the thing that your brain hooks into and uses to tell you it isn't enough yet).

> Tastes and looks like beer I have tried almost every major non-alcoholic beer in the U.S., and none of them truly taste exactly like beer.

> I have tried almost every major non-alcoholic beer in the U.S., and none of them truly taste exactly like beer.

Agreed, but if you drink them exclusively for a few weeks, your taste buds and brain will reframe around them, and it'll cease to be a problem. I did this with Brewdog's Punk AF, and after 2 weeks on that, most non-alcoholic beers triggered my brain's "I'm drinking beer!" response.

It's a lot of work for overpriced soft drinks, and isn't for everyone.

Also, I'm back to drinking real beer again anyway.

Re: New gel breaks down alcohol in the body

#197
post #141
post #55

Earlier quoted context omitted.

What about all the other negative impacts though - like liver impact and blood pressure. Isn’t it better to just moderate your drinking rather than drinking to excess and then dialing back the feel of it with broccoli?

Agree. Of all the negatives, I think diminished sleep is the one that doesn’t get enough attention. It’s superficial sleep at best. You’re up peeing 3,4,5 times a night. You never enter REM sleep. You’re dragging the entire next day. All to do it over again to your body the next day? Of the people that I know that drink actively almost every day, they look like shit, and lack motivation. Their body is crying out for…

not a sleep expert by I think the biggest impact is on deep sleep, not REM

Re: New gel breaks down alcohol in the body

#198
post #188

Earlier quoted context omitted.

Hangovers are a good part caused by by the body reacting to the "damage" that alcohol does: - Alcohol loosens the blood vessels, whereas a lot of the effects of a hangover are caused by the body then "over-constricting" when the aclohol goes away, causing headaches and nausea. The cause of the headache is similar for a brain-freeze from too much ice cream causing the veins in your neck and throat to constrict, though…

I'm sure I'm not the only one who just really enjoys the taste of alcohol and would love a way to drink more of it without its effects, both the "positive" and the negative side. It's genuinely one of my big wishes! I'd pay 5x the normal price for a bottle of whisky that neither has the "good" nor "bad" parts, as if it was water but with the same taste.

I don’t think they do whiskey yet, but ISH Spirits makes some tasty alcohol free products.

https://ishspirits.com/

Re: New gel breaks down alcohol in the body

#200
post #59

Earlier quoted context omitted.

Great suggestion. There is also Kislip, which seems to be based on probiotics and, like DHM, also helps metabolize acetaldehyde. Acetium (a Finnish product) also claims to lower acetaldehyde, but that might be a localized effect (mouth/nasopharynx + GI tract).

Zbiotics gives you genetically modified probiotic bacteria that secrete ALDH into your gut.

I'm not sure how that's helpful. It looks like ALDH is responsible for breaking down acetaldehyde. However, the pathway for ethanol to become acetaldehyde happens primarily in the liver with ADH. So while this may flood your stomach with ALDH, that's mainly only useful in the blood stream after alcohol is metabolized right?

Is the theory here that because the digestive tracks is a large organs filled with blood the resulting ALDH would interact?

My next question is do these, and how many, probiotic bacteria survive the acid wash of the stomach?

Are there studies around this?

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