It really is amazing. We were thiiiiiiis close to having a generation that wasn't addicted to nicotine for the first time in hundreds of years (like, since trade between North America and Europe really became a thing) and these guys pulled this thumb drive that tastes like cotton candy out of nowhere and every young person is just jonesing . And the regulatory/public opinion environment isn't what it was in the 80s a…
But what’s so bad about nicotine? Is it any worse than caffeine? I’m genuinely curious, because isn’t tar and carbon monoxide the dangerous byproduct of smoking, not the nicotine?
Here is one like that: ~500k individuals, vaping has an odds ratio of 1.33 (95% CI = 1.14–1.56) for heart attacks compared to non-smoker/non-vapers.
https://www.sciencedirect.com/science/article/abs/pii/S01675...
[edit] To compare that to caffeine, this study does not see a significant risk increase for coffee drinkers. So it seems that vaping is objectively more harmful:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940396/
[edit2] And an umbrella review, because I like them a lot: This shows that negative effects of high coffee intake mostly disappear when controlling for smoking. Note this paper has a correction, which I think is a great sign of credibility. https://www.bmj.com/content/359/bmj.j5024