Earlier quoted context omitted.
By becoming completely insular, you lose the ability to innovate, as you cater to a subset of consumers and as such aren't being pushed to test the limits of the existing status quo. For example, look at what happened to Sony - they were a darling of the Consumer Technology space and the Apple of the 1990s-early 2000s, but because they concentrating on the Japanese market at the expense of the global market, they fel…
I think the key word there was 'primary'. I think it's okay to have a main audience in mind that isn't the entire world.
Increasingly, American companies cannot expect to succeed internationally on the strength of brand alone, if they are not willing to customize their product and service offerings to meet local requirements.