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Launch HN: Volta Labs (YC W19) – Easier sample prep for genomics

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Re: Launch HN: Volta Labs (YC W19) – Easier sample prep for genomics

#31
post #28

Congrats Udayan on the launch! It’s really neat to see the open-face nature of this product as compared to others doing EWOD with a second immiscible phase / a glass top plate that the droplet is squished under — makes it much easier to do IO to the chip. Are the chips disposable, to accomodate contamination constraints, or is there some on-site surface reconditioning that we can do to refurb the chips? Interesting t…

Hi Dash! The system uses a disposable plastic consumable that gets replaced after each run. In terms of design trade offs, its not just a electrowetting system. It employs complex magnetic manipulation, thermal controls and other forms of sample manipulation. We had to work under these constraints.

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Re: Launch HN: Volta Labs (YC W19) – Easier sample prep for genomics

#32

The Volta Labs employee reviews on GlassDoor paint a picture of a high functioning team feeling crippled by absent or dysfunctional management. There are some high ratings but to my eye they look like they were probably written by management. Are you confident you can launch and support a complex innovative product successfully with an apparently disgruntled and depressed technical team?

Employee reviews are a very underrated way to judge a company. Especially one that offers breakthrough tech

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Re: Launch HN: Volta Labs (YC W19) – Easier sample prep for genomics

#33
This is awesome. I am highly interested in the BioTech space and happened to work with electro-wetting for zero gravity space applications almost 10 years ago!

This is such a cool application of the tech. Everything is accelerating in biotech.

We were using electro-wetting as a low power heat pipe on the Space Station, since heat doesn’t dissipate the same way there as it does on Earth. The tech I built with some engineers used these tiny DC to DC high voltage transformers that would step up the voltage from the 18V power supply to something like 450V on the circuit board to enable the electro-wetting heat pipes to move water droplets.

Would love to chat sometime if you are ever interested.

For reference, our very scrappy POC for the space station: https://ntrs.nasa.gov/api/citations/20190006008/downloads/20...

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