221–230 of 247 posts
Earlier quoted context omitted.
In much of the world (weighted by humans) people use squat toilets. So, problem is solvable by installing one after your CRISPR tail procedure.
What kind of tail are we looking at? One like a bunny or something like a cat?
I believe this suggests that we could CRISPR an embryo to knock-out the offending Alu element in the TBXT gene and the child will develop a tail.
Link to the open access article : https://www.nature.com/articles/s41586-024-07095-8 If you scroll to the bottom check out how long this article went into peer review: almost 3 years! Three years can get you a PhD in UK. Received 14 September 2021 Accepted 19 January 2024 Published 28 February 2024
Is that normal? I imagine the poor bastards wanted to put it on their CV for their next job.
Median time is 268 days to acceptance at Nature. So this article was closer to 1000 days, above average.
If we're doing germline edits, the obvious thing to fix first is vitamin synthesis. There are a bunch of useful things other living things synthesise from first principles, and we don't so we need to eat something that has already synthesised the thing we wanted, and we can't cook or preserve it in any way that destroys the material we needed or it won't work. That's what scurvy is, a tree or a lizard just makes its…
If we are on this topic then we need to discuss a genetically modified gut microbiota. We do not need to edit genetically ourselves for some pityful vitamins. Microbiota could give us all we want. It could enable us to digest plastic, so we could eat food without removing its packaging. We could reduce severity of our waste problems by digesting plastic into relatively harmless poop.
I believe this suggests that we could CRISPR an embryo to knock-out the offending Alu element in the TBXT gene and the child will develop a tail.
At what age would it be too late to try this? Asking for a friend...
Earlier quoted context omitted.
At what age would it be too late to try this? Asking for a friend...
It needs to be done at the embryonic stage before cell division so that as the cells replicate, they inherit the desired changes. The technology isn't quite there yet to transfect every single cell in an adult body with a virus containing the desired genetic modifications. Also, I can only imagine the downstream of effects of the body transcribing this modified dna in a fully-developed human. Have you ever seen the m…
Earlier quoted context omitted.
Nature does not refactor. There's the laryngeal nerve somewhere in the neck of mammals that has to go around a blood vessel. On Giraffes, this runs all the way down the neck, around said blood vessel, than back up, all that just to connect two places in the upper neck that are inches apart. Evolution writes the ultimate spaghetti code. More info: https://berto-meister.blogspot.com/2011/08/unintelligent-des...
God must be a frontend developer.