Oh, huh, I have always noted an odd ruddiness/doughiness as being common to certain ASD individuals I know. I always just attributed it to being overweight etc but I wonder if that’s the vasopressin fluid imbalance.
Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
91–100 of 106 posts
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#92Earlier quoted context omitted.
Exactly right. Reducing dietary fats is "as good" advice as it was or ever will be.
I'm sure you are responding with good intentions, that some 'healthy' fats are needed in a healthy diet. The demonization of fat is wrong. But Also Eating 5lbs of Ribs every day and weighing 300 lbs is not healthy. Same with salt. The 'healthy' amount of salt is a U curve. You can have too little, and too much. It's just in the typical American diet, there is so much Fat and so much Salt, that most people area alread…
> Eating 5lbs of Ribs every day and weighing 300 lbs is not healthy.
If you started at normal weight and ate 5lbs of ribs (or, till satiety) every day, with as much butter as you'd like, but ZERO carbs or artificial sweeteners, you'd never gain weight, much less get to 300 lbs. That's my point.
But don't believe me - this experiment has been done many times.
Google: "zero carb" or "Banting diet."
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#93Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#94Earlier quoted context omitted.
It's actually the individual's responsibility to develop an understanding of how one determines what is trustworthy and what isn't trustworthy, and they they do their best to develop that. For example, if someone lies, they are caught lying, the evidence is presented but a person doesn't care or put any weight on that someone lied - well, they are going to rank that person or an organization they are running or still…
you mean like the "science" and "experts" paid off by the sugar industry to promote sugar for 50 years while demonizing fat?
Who was promoting sugar, exactly? This is an extraordinary claim that requires extraordinary proof.
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#95Earlier quoted context omitted.
When left handedness was seen as a disorder and students who used their left hand were beaten, rates of this disorder were a few percent. When the idea of left handedness became mainstream, rates skyrocketed and we know the base rate is about 10%. Homosexuality was considered a disorder in the DSM until 1974. Self-reported rates of homosexuality have skyrocketed since then. Most likely explanation is that the true ba…
I wrote a response that argues against your hypothesis, and then I realized ... "do I really know what I'm saying? Or are these my preconceptions and biases?" > and we know the base rate is about 10%. Sinister. I think it would be cool to be left-handed in a country where the language is written from right to left.
> Sinister.
A dexterous response, to be sure. ;)
I find it interesting that the rates of a whole bunch of these uncommon-but-still-prevalent differences seem to cluster around 10%. I can't help wondering if it stems from prehistoric humans living in small group of 20-30, so each band would have on average 2-4 of each, giving the group a wider range of capabilities than they would otherwise have.
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#96I’ve theorized in my book _Fat Gas_ that vasopressin levels are tied to elevated indoor CO2 levels. Would not be at all surprised if these novel social conditions stem from not going outside enough and from poorly ventilated buildings (especially gyms and conference rooms) and transport (planes trains and automobiles each routinely exceed 1000 ppm from everybody’s lungs).
With respect, this does not sound rooted in factual basis. Anyone who has taken physiology and been educated in anesthesia knows that there are numerous factors and feedback loops that decouple your theory of a direct link between ambient pCO2 and "vasopressin levels".
I'd like to hear a more detailed explanation on how you feel it overrides compensatory mechanisms in ventilation, with subsequent breakdown in metabolic compensation of acidemia, and how you override negative feedback loops in the RAAS system including inhibition of ANP excretion, unless you theorize it is blunted at the renal level and natriuresis becomes down regulated in this scenario.
Or basically if you want to reframe how everyone sitting in a house has subclinical SIADH I would be eager to hear a more detailed explanation.
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#97Now that's some serendipitous reading. I've been on the hunt for possible mechanisms (for further study) as to why last year after trying an SSRI (escitalopram), to treat an anxiety disorder co-morbid to my ASD, that I ended up in the hospital in a hypertensive crisis. Was an all around terrible experience and I hope one day I can figure out WTF happened to me. Interestingly the BP rise seemed to be mostly diastolic…
ive been doing my own research for similar reasons (zoloft in my case), although i fortunately did not end up in a hospital. my girlfriend works with autistic children and swears i have ASD but I havent gotten around to being officially diagnosed, nor am i fully convinced of her claim. if you dont mind sharing, what genome sequencing service did you use? granted i havent looked too far but a lot of services i saw wer…
Oh the popular WGS services are a borderline scam. I fell for their BS unfortunately so are out a few hundred euros. I don't expect to see results for 12 months or more (if ever).
In the end I found a local company that does WGS sequencing and they are a lot more reasonable to deal with, maybe 1.5-2x the price. So perhaps look for smaller providers, they are all just reselling time on the same Illumina machines.
In your case, just confirming, your blood pressure is otherwise normal and you experienced an episode of severe hypertension after starting Sertraline (zoloft)? No other contraindicated medications? No indications of a bipolar/mania or something of that nature? I've talked to maybe 3x other people now who've had similar experiences (after scouring the internet), and the only commonality I've found is ASD.
This is a bit of a pet project of mine, so if you want to chat about ASD shenanigans, please reach out to: asd.shenanigans@mailbox.org
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#98Earlier quoted context omitted.
I wrote a response that argues against your hypothesis, and then I realized ... "do I really know what I'm saying? Or are these my preconceptions and biases?" > and we know the base rate is about 10%. Sinister. I think it would be cool to be left-handed in a country where the language is written from right to left.
> Sinister. A dexterous response, to be sure. ;) I find it interesting that the rates of a whole bunch of these uncommon-but-still-prevalent differences seem to cluster around 10%. I can't help wondering if it stems from prehistoric humans living in small group of 20-30, so each band would have on average 2-4 of each, giving the group a wider range of capabilities than they would otherwise have.
Something influenced by 2 double recessive genes will occur ~1/8 of the time in a population where the recessive gene is common.
Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#99Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]
#100Earlier quoted context omitted.
My nephew is on the spectrum (fairly severely). His mother and father are obsessed with air quality and used filtration and forced ERVs for the entire pregnancy and upbringing. Please do not make such strong medical claims without any scientific backing, it is quite harmful to kids with autism and their parents who are already overwhelmed with quackery.
the guy wrote a book on it. so far his evidence far exceeds yours, which is none.
Can't tell if this is sarcasm or not...