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Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

med.stanford.edu

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Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#31

Post by pc86 »

squigz wrote: post #25
mchannon wrote: post #8

I’ve theorized in my book _Fat Gas_ that vasopressin levels are tied to elevated indoor CO2 levels. Would not be at all surprised if these novel social conditions stem from not going outside enough and from poorly ventilated buildings (especially gyms and conference rooms) and transport (planes trains and automobiles each routinely exceed 1000 ppm from everybody’s lungs).

Could you elaborate on what you mean by "novel social conditions"?

ASD diagnoses have skyrocketed in the past few decades (years?) with no clear cause. I'm just old enough to remember a childhood without cell phones - we didn't have a computer in my house until middle school but we were lower income than most of my friends - and people are definitely inside more and outside less than they were when I was 8 or 9 years old.

It seems like a plausible theory.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#32

Post by pc86 »

tootie wrote: post #14
mchannon wrote: post #8

I’ve theorized in my book _Fat Gas_ that vasopressin levels are tied to elevated indoor CO2 levels. Would not be at all surprised if these novel social conditions stem from not going outside enough and from poorly ventilated buildings (especially gyms and conference rooms) and transport (planes trains and automobiles each routinely exceed 1000 ppm from everybody’s lungs).

I mean, it's cars. Fossil fuel combustion in general, but car exhaust in particular.

Cars don't lead to increased indoor CO2 levels.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#33

Post by pc86 »

polishdude20 wrote: post #17
mchannon wrote: post #8

I’ve theorized in my book _Fat Gas_ that vasopressin levels are tied to elevated indoor CO2 levels. Would not be at all surprised if these novel social conditions stem from not going outside enough and from poorly ventilated buildings (especially gyms and conference rooms) and transport (planes trains and automobiles each routinely exceed 1000 ppm from everybody’s lungs).

How would this be true for planes? They're constantly being fed fresh air from the engines during flight.

It's true for every other mode of transport but objectively false for planes in flight. However, I'd be curious to see the average when including time sitting on the ground, taxiing, etc., and how that much lower speed affects circulation.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#34

Post by sp332 »

meindnoch wrote: post #12
Solvency wrote: post #11

Earlier quoted context omitted.

citation.

Google. https://hms.harvard.edu/news/cracking-fever-autism-mystery

Your citation looks fine, but telling people to Google for citations is just pointing them straight at spam.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#35

Post by azinman2 »

pc86 wrote: post #31
squigz wrote: post #25

Earlier quoted context omitted.

Could you elaborate on what you mean by "novel social conditions"?

ASD diagnoses have skyrocketed in the past few decades (years?) with no clear cause. I'm just old enough to remember a childhood without cell phones - we didn't have a computer in my house until middle school but we were lower income than most of my friends - and people are definitely inside more and outside less than they were when I was 8 or 9 years old. It seems like a plausible theory.

Lots of other things have changed, including, people are having kids older (known correlate), the DSM definition changed, and the general awareness has radically increased.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#36

Post by jplona »

pc86 wrote: post #31
squigz wrote: post #25

Earlier quoted context omitted.

Could you elaborate on what you mean by "novel social conditions"?

ASD diagnoses have skyrocketed in the past few decades (years?) with no clear cause. I'm just old enough to remember a childhood without cell phones - we didn't have a computer in my house until middle school but we were lower income than most of my friends - and people are definitely inside more and outside less than they were when I was 8 or 9 years old. It seems like a plausible theory.

I've always understood the increase in diagnoses to be more about increased awareness than about a change in human behavior.

E.g. it looks like autism wasn't defined as a spectrum in the DSM until either 1994 or 2000: https://www.spectrumnews.org/news/evolution-autism-diagnosis....

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#38

Post by Solvency »

kiba wrote: post #16
Solvency wrote: post #10

Earlier quoted context omitted.

Or dense urban housing. But we're not allowed to criticize that, right. Homes with yards and green space are evil!

Actually, roads and parking garage and driveways take up spaces that could be used for parks and greenery. You could have tramways with grassy cover, for example. Every time when I drive to anywhere, I am surrounded by five lane stroads. By removing all these spaces for cars, you could add back in green spaces. Houses with backyards can still exists, but they will be closer together. Parks will be closer and more acc…

when did I say anything about cars? I say to hell with all cars, replace everything with bicycles and electric scooters. Then we can use lightrail to connect larger communities to one another.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#39

Post by Solvency »

klausa wrote: post #22
Solvency wrote: post #10

Earlier quoted context omitted.

Or dense urban housing. But we're not allowed to criticize that, right. Homes with yards and green space are evil!

You’ll have lower CO2 levels in a dense urban housing with windows open, than in a home in the middle of nowhere with the windows closed. The issue isn’t the higher amount of CO2 in the ambient air in the cities (AIUI it is; marginally; but it doesn’t matter); it’s that CO2 is very good at concentrating in enclosed spaces.

literally only in the currently designed world dominated by large cars, which is equally outrageous. Nuke the entire nonsense system we have, let people have homes in yards, and force everyone to get around on bicycles and electric scooters and electric accessibility carts.

Re: Vasopressin deficiency: driver of social impairment and fluid imbalance in ASD? [pdf]

#40

Post by [deleted] »

mchannon wrote: post #8

I’ve theorized in my book _Fat Gas_ that vasopressin levels are tied to elevated indoor CO2 levels. Would not be at all surprised if these novel social conditions stem from not going outside enough and from poorly ventilated buildings (especially gyms and conference rooms) and transport (planes trains and automobiles each routinely exceed 1000 ppm from everybody’s lungs).

[deleted]
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