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Surgeons transplant pig kidney into a patient

nytimes.com

81–90 of 122 posts

Re: Surgeons transplant pig kidney into a patient

#81
post #21

What happens to other parts from these genetically modified pigs? Can some be used for other transplants? Can rest be eaten?

I don’t think you’d want to eat severely genetically modified pigs though. Who know what kinds of viruses can make the jump to humans in a chimera like that. Ideally those pigs would be kept in some kind of sterile biohazard location and their bodies would ideally be incinerated afterwards.

Do we also do that to the organ recipient?

Re: Surgeons transplant pig kidney into a patient

#82

Earlier quoted context omitted.

I don’t think you’d want to eat severely genetically modified pigs though. Who know what kinds of viruses can make the jump to humans in a chimera like that. Ideally those pigs would be kept in some kind of sterile biohazard location and their bodies would ideally be incinerated afterwards.

Do we also do that to the organ recipient?

Well the organ recipient’s body is now an incubation chamber for pig human virus crossovers. But it’s a human, so we deal with the risks. Hopefully he doesn’t deal with a lot of pigs on a daily basis.

Re: Surgeons transplant pig kidney into a patient

#83

Earlier quoted context omitted.

Disagree. The "choose life at any quality of life" ideology causes immense suffering. Ideally in the long run, this is a step in the direction of keeping people alive with a higher quality of life, but that's unlikely to be this first person's experience.

Sure, but is a low quality life worse than oblivion? Even if you're not 25 and healthy and wealthy and happy, I think life is still worth living. Plus, if the suffering experienced by this patient helps cause someone else (or many someones else for centuries to come) to have a higher quality of life, one person's suffering can buy a lot of QALYs. Alternatively if as my mother tells me, I'm doomed to an eternity of un…

This viewpoint comes about from a lack of empathy/knowledge of the type of pain that would want someone to seek death.

As a general rule of thumb, trying to decide someone’s own stream of consciousness is assholeish behavior.

Re: Surgeons transplant pig kidney into a patient

#84
post #77

I would like to have more details on the list of genetic modifications needed to make the kidney implantable in an human without being rejected/attacked by the immune system.

I'm sure (99.9%) its patented, so you can find and read those patents. i expect there should also be a list of publications in it what it was based on. its probably heavy biology / chemistry though (i know, as I've been researching other gene modification patent stuff before)

Re: Surgeons transplant pig kidney into a patient

#85

It's hard for me to imagine the bravery it takes to sign up for this -- even if you're dying already, something like this is unlikely to result in a peaceful final days on earth (between being a science experiment, the media, optional major traumatic surgery, etc...). The folks undergoing this are incredibly admirable.

The patients, the nurses, the surgeons, doctors, researchers.

Literally magic. The Indian god Ganesha for example has a head of an elephant and we humans are doing something similar.

What an amazing species we are when we are doing something positive.

Re: Surgeons transplant pig kidney into a patient

#87
post #32

Earlier quoted context omitted.

I didn’t realize you had to take lifelong immunosuppressants with human organs as well. That makes this indistinguishable, provided it keeps working.

I'm curious, when did you think patients had to take immunosuppressants?

Autoimmune diseases like lupus

Re: Surgeons transplant pig kidney into a patient

#89

Earlier quoted context omitted.

The alternative is certain death so not a lot to choose from

Disagree. The "choose life at any quality of life" ideology causes immense suffering. Ideally in the long run, this is a step in the direction of keeping people alive with a higher quality of life, but that's unlikely to be this first person's experience.

I'd wager such choices are highly personal, and different people will weigh things differently. I've seen quotes from people undergoing dangerous and highly experimental treatments stating that they felt happy to help medicine learn, even at significant cost to themselves. The patient in this case said much the same.

Nonetheless, I do generally agree with you. I've seen several articles about how doctors die very differently than most people (they often have DNRs and far fewer end-of-life interventions).

Re: Surgeons transplant pig kidney into a patient

#90
post #73

Earlier quoted context omitted.

Disagree. The "choose life at any quality of life" ideology causes immense suffering. Ideally in the long run, this is a step in the direction of keeping people alive with a higher quality of life, but that's unlikely to be this first person's experience.

Doctors (and society) should not be encouraging this mentality. But individuals surely have the freedom to think like this and make decisions accordingly.

Why? My doctor's job is to give me health advice and treatment not moral advice. And it's none of society's business so really they shouldn't be chiming in anyway.
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