The author is periodically active on HN: https://news.ycombinator.com/user?id=devaboone
Story of Vitamin D Toxicity (2022)
81–90 of 170 posts
Re: Story of Vitamin D Toxicity (2022)
#82Earlier quoted context omitted.
The widely used daily recommended amounts of Vitamin D (600 IU in the US and Canada) are wrong, by a factor of 10, and based on a math typo that no one caught until 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ . I guess many still don't realize this fact. "We call public health authorities to consider designating as the RDA ... around 8000 IU for adults"
Isn’t the issue made worse by the fact that Vitamin D absorption is way lower if not in conjunction with Vitamin K? Or is this a myth?
Vitamin K is needed so that calcium doesn't build up in the vessels but goes to the bones where it's supposed to be. But, taking D and K at the exact same time reduces the absorption of D.
Re: Story of Vitamin D Toxicity (2022)
#83Earlier quoted context omitted.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811610/ Figured people can Google, all I bring is awareness this is widely overblown, having taken myself, for therapeutic purposes, upwards of 100k IU per day for months without doctor supervision (but doing it correctly, with a very low calcium diet). People take vit D megadoses for autoimmunity, with significant success, but I'm not discussing this here.
Can you comment on why the low calcium diet matters and what is considered low calcium? Doesn’t that lead to other issues? I have been diagnosed with some autoimmunity issues and would love to try this. How did you identify that vitamin d might help with yours?
It really means complete elimination or drastic reduction in anything high in calcium, even water can have quite a bit. But this was, again, with extremely high doses. I don't currently follow the protocol, as I do other things, but I sometimes take high doses for a few days.
When I had my first major flare-up, I tested at 7ng/dl (near bottom half of the severe deficiency range). That's what lead me to pay attention to this subject.
Re: Story of Vitamin D Toxicity (2022)
#84I struggle to believe that a physician told her to take 5000 IU of vitamin D daily for 5+ years. This is nearly 10x canada's recommended winter time dose for adults under 70. After years of struggling with severe joint pain and mental fog/depression, among other things it was discovered that I had critically low vitamin D. They prescribed the 5000 dose but told me at least 10 times how I should NOT continue this high…
I've been on 10,000 IU daily for longer than that, its the only thing that brought me up into the normal range, and my doctor just does periodic blood tests (for either it going high or any signs of the problems that can come from it being too high) and has it listed with my current medication in my chart. The miscommunication seems to be in her care team: symptoms associated with high vitamin D occurred, she was kno…
I take 12k IU of D3 + K2 to keep my calcium and vitamin D levels adequate.
Also, I have anemia of unknown etiology.
Not recommended for everyone, but supplementation should be calibrated with regular blood tests. This should be the standard of maintaining homeostasis.
Re: Story of Vitamin D Toxicity (2022)
#85Earlier quoted context omitted.
The fear of vitamin D overdose is GREATLY overblown, people recover even with overdose with ridiculous (2 MILLION) units over several weeks, anyway, it's strange how much fear has been manufactured over this particular "vitamin".
Source?
> The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D (usually in the range of >50,000-100,000 IU/d for months to years).
https://www.mayoclinicproceedings.org/article/S0025-6196%281...
Re: Story of Vitamin D Toxicity (2022)
#86I struggle to believe that a physician told her to take 5000 IU of vitamin D daily for 5+ years. This is nearly 10x canada's recommended winter time dose for adults under 70. After years of struggling with severe joint pain and mental fog/depression, among other things it was discovered that I had critically low vitamin D. They prescribed the 5000 dose but told me at least 10 times how I should NOT continue this high…
5000 IU daily for 5 years is crazy. Vit D is fat soluble and will stay in the body a long time. Short term big bursts if you're deficient are probably fine, but more than 2000 IU a day for years makes me nervous. for comparison, Vit C is water soluble and you can slam Emergen-C 2000 mg packets without issue as long as you're hydrated and have working kidneys -- you'll pee it out.
> The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D (usually in the range of >50,000-100,000 IU/d for months to years).
https://www.mayoclinicproceedings.org/article/S0025-6196%281...
Re: Story of Vitamin D Toxicity (2022)
#87(2020) and not the first time I see this link on HN actually
Vitamin D is reheated and presented as revolution every few years. Yes, everyone should take vitamin D supplements, but too much vitamin D is very dangerous. Everyone should regularly get tested for their vitamin D level as well. It's cheap. It's easy. It's quick.
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Re: Story of Vitamin D Toxicity (2022)
#88a recently reported case in the uk
Re: Story of Vitamin D Toxicity (2022)
#89I order vitamin D directly from the sun, light-fast, gradual and free delivery
Re: Story of Vitamin D Toxicity (2022)
#90I'm currently taking 10,000IU per day in an effort to control psoriasis, but it's a bit of guess work really and trying stuff to see what helps. It's somewhat annoying that I've had a dermatologist order some blood tests, but they were only targeted for whether I can safely take acitretin (a retinoid). I wish there were cheap home-tests for various blood levels of minerals and vitamins like there are for things like…
Taking vitamin D daily did wonders for my psoriasis. Over the years it had gotten to the point where I was breaking out in patches all over my body, and only getting worse as time went on. I went from like 2% coverage to 20%.
Started taking vitamin D and am now back at 2% (where it has sat for 4 years now since I started).