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Story of Vitamin D Toxicity (2022)

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Re: Story of Vitamin D Toxicity (2022)

#41

Post by chimeracoder »

JohnMakin wrote: post #11
alyandon wrote: post #9

Earlier quoted context omitted.

I was diagnosed with low serum levels of vitamin D so I take daily supplements. The general guidance for my condition is 1000 IU daily. At one point in time, I discovered I had been taking 5000 IU/day instead of 1000 IU/day for about 180 days because of the bottles being identical except for the dosage printed in Flyspeck Times Roman 4pt. Fortunately, I alerted my doctor and a followup blood test confirmed I was stil…

Yea, the dosage and labeling for sure needs work. I see 2000 IU doses regularly sold in stores and the bottle says you can take 2/day. Obviously no doctor would recommend that for anyone not sick. I also get regular blood tests since, I'd guess most people using supplements do not.

> Yea, the dosage and labeling for sure needs work. I see 2000 IU doses regularly sold in stores and the bottle says you can take 2/day. Obviously no doctor would recommend that for anyone not sick.

That is simply not true. Doctors do recommend 2000-4000 IU for healthy patients all the time.

Re: Story of Vitamin D Toxicity (2022)

#42

Post by bousenta »

hombre_fatal wrote: post #28
hammock wrote: post #19

Earlier quoted context omitted.

The widely used daily recommended amounts of Vitamin D (600 IU in the US and Canada) are wrong, by a factor of 10, and based on a math typo that no one caught until 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ . I guess many still don't realize this fact. "We call public health authorities to consider designating as the RDA ... around 8000 IU for adults"

Can you corroborate their opinion with other sources? It’s not very evidence based.

[flagged]

Re: Story of Vitamin D Toxicity (2022)

#43

Post by Novosell »

lambdaba wrote: post #36
miduil wrote: post #31

Earlier quoted context omitted.

Source?

> The knowledge about toxicity from hypervitaminosis D in terms of dosage and duration is limited. Because of the high heterogeneity in reported amounts of vitamin D intoxication cases, it is not possible to calculate a reliable mean value that will invariably induce toxic effects. The highest daily dose hitherto reported in the literature is about 2,000,000 UI/day that has led to intoxication in a couple of months >…

Quotes without a source?

> 1mg will instantly kill you.

Re: Story of Vitamin D Toxicity (2022)

#44

Post by mettamage »

hammock wrote: post #19
JohnMakin wrote: post #4

I struggle to believe that a physician told her to take 5000 IU of vitamin D daily for 5+ years. This is nearly 10x canada's recommended winter time dose for adults under 70. After years of struggling with severe joint pain and mental fog/depression, among other things it was discovered that I had critically low vitamin D. They prescribed the 5000 dose but told me at least 10 times how I should NOT continue this high…

The widely used daily recommended amounts of Vitamin D (600 IU in the US and Canada) are wrong, by a factor of 10, and based on a math typo that no one caught until 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ . I guess many still don't realize this fact. "We call public health authorities to consider designating as the RDA ... around 8000 IU for adults"

This should be its own HN submission. I want a discussion on this.

Edit: nevermind, it was posted 2 times already [1, 2].

[1] https://news.ycombinator.com/item?id=24768721

[2] https://news.ycombinator.com/item?id=15867918

Re: Story of Vitamin D Toxicity (2022)

#46

Post by lambdaba »

Novosell wrote: post #43
lambdaba wrote: post #36

Earlier quoted context omitted.

> The knowledge about toxicity from hypervitaminosis D in terms of dosage and duration is limited. Because of the high heterogeneity in reported amounts of vitamin D intoxication cases, it is not possible to calculate a reliable mean value that will invariably induce toxic effects. The highest daily dose hitherto reported in the literature is about 2,000,000 UI/day that has led to intoxication in a couple of months >…

Quotes without a source? > 1mg will instantly kill you.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811610/

Figured people can Google, all I bring is awareness this is widely overblown, having taken myself, for therapeutic purposes, upwards of 100k IU per day for months without doctor supervision (but doing it correctly, with a very low calcium diet). People take vit D megadoses for autoimmunity, with significant success, but I'm not discussing this here.

Re: Story of Vitamin D Toxicity (2022)

#47

Post by [deleted] »

Traubenfuchs wrote: post #34
raverbashing wrote: post #25

(2020) and not the first time I see this link on HN actually

Vitamin D is reheated and presented as revolution every few years. Yes, everyone should take vitamin D supplements, but too much vitamin D is very dangerous. Everyone should regularly get tested for their vitamin D level as well. It's cheap. It's easy. It's quick.

[deleted]

Re: Story of Vitamin D Toxicity (2022)

#48

Post by bitshiftfaced »

readthenotes1 wrote: post #27
hammock wrote: post #19

Earlier quoted context omitted.

The widely used daily recommended amounts of Vitamin D (600 IU in the US and Canada) are wrong, by a factor of 10, and based on a math typo that no one caught until 2017: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ . I guess many still don't realize this fact. "We call public health authorities to consider designating as the RDA ... around 8000 IU for adults"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210929/ Is the article that talks about the miscalculation

Interesting that they found that to meet the target threshold, you'd need to take well over the "tolerable upper intake" or 4000 IU.

Re: Story of Vitamin D Toxicity (2022)

#50

Post by bradfa »

Traubenfuchs wrote: post #34
raverbashing wrote: post #25

(2020) and not the first time I see this link on HN actually

Vitamin D is reheated and presented as revolution every few years. Yes, everyone should take vitamin D supplements, but too much vitamin D is very dangerous. Everyone should regularly get tested for their vitamin D level as well. It's cheap. It's easy. It's quick.

My USA health insurance used to cover the blood test for vitamin D, but stopped about 10 years ago. Now to get a blood test it's somewhere in the $70-100 extra range if I want to get that in addition to a normal yearly physical blood panel.

Yes, that prices isn't that much for your health, but if you decide you want to take a LOT of vitamin D then you need to comprehend the blood test costs.

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