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Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

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Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#51

Post by calderarrow »

Give that money to someone close to you who can hold you accountable — hell, I’ll do it if you need — but you’re going to be earning every dollar of that over the next year by counting calories. Here’s how:

It’s approximately 5000 calories per pound of weight that you want to lose. 30 pounds * 5000 calories = 150k calories to lose 30 pounds. That’s pretty close to $100k Pay yourself to count calories, $1 per calorie. Track everything. Every meal, every snack, everything you put into your body. Every week, add up the total calories consumed and subtract the total amount from your weekly “maintainence” calories. To calculate that, multiply your current body weight by 16 or 18, depending whether you exercised that day. For instance, if you weigh 200 pounds, you should eat about 3200-3600 calories daily to maintain that weight, closer to 3200 if you don’t exercise, 3600 if you do. Every week, pay yourself $1 for every calorie you burned, re-weigh yourself, and repeat.

No exercise needed, but that will definitely accelerate the process, but only so much. It took months to get you here, so expect to spend months to get you out.

Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#53

Post by InTheFutureRob »

Carnivore is FOOLISH. There is no Scientific evidence whatsover that it benefits anything aside from short term weight loss, at the detriment of your health. I would get my whole genome sequenced and get a genetic counselor. Get a personal trainer and an expert on human performance (Get tested from athletic labs you can measure your VO2 max, RMR, Body composition and create a workout routine optimizing for longevity and health) Eat a varied diet rich in Vegetables like Broccoli, spinach, Kale..Carrots (8 servings every dinner 365 days a week), healthy fats like Extra virgin olive oil, Wild Salmon, Sardines, avocadoes, ALmonds, nuts seeds. Spend 1000-1500 a month on groceries if you have to. Get enough sleep, reduce stress, keep purpose and and social connection. Keep up to date with your screenings (Blood test measure Hemoglobin h1c, LDLc, HDLc, get a NMR lipoprofile if you want to), get a private doctor if you have to that is more like a personal trainer and optimizes health rather than just treat disease. Also consider getting on Metformin, Rapamycin and possibly Statins if your LDL Triglycerides etc are high. Avoid too much sun exposure, toxins, polluted air. Get a air purifier...And consider GLP-1 agonist.

Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#54

Post by garciasn »

htrp wrote: post #47
garciasn wrote: post #36

Have your wife file for divorce after you find out she’s been cheating on you for 18 months and been planning for this eventuality since day 1 of her affair. Oh and she’ll have spent $300K in 11 months prior to the divorce. I’m already $30K down in legal fees on top of it all. The one bit of good news is that I lost 1/3 of my total body weight since Thanksgiving.

Are you ok mate?

I never know how to answer that question, if I’m being honest.

I’m functional. But, no, I’m not ok.

Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#56

Post by throwawayfitpla »

Throwaway since it’s kinda personal. I was in nearly the same position last Jan. I started my journey when I told myself “I’m too rich to be fat”.

Here’s the game-plan I’ve followed myself to lose 50lbs and turn my bloodwork from highly concerning to near textbook.

1. See a clinic or doc who will prescribe Mounjaro / Ozempic or the compound pharmacy versions (tirzepatide, semaglutide). This will take all the weight off with little effort. You’ll suffer nausea and other side effects but it’s reactive instead of proactive. Costs about $1k/month. No need for nutritionists or special meal plans at first (not a bad idea though!), you will restrict calories on your own. If you are reticent to take these drugs diabetes may force your hand later. For me it was either now with the option to stop, or later and quite likely forever.

2. See a TRT doc (if male) and make sure your hormones are “balanced”. Most will put you on the very high end of Testosterone range, and may give you HGH or other enhancements. Costs vary, but $500/month should cover everything. My T went from low for an elderly man (220) to the high end of a younger one (950). I also take HCG for aesthetics (ball size) and to maintain some natural production. My doc is willing to give me Deca, Anavar, and others to meet my goals, but I’m not trying to be Hollywood jacked or ripped so I pass.

3. Forget a regular gym membership, that’s too proactive. Go with regular 1-1 training sessions, starting slow with 3/week. FlexIt and other remote training services are great for motivation. You can roll out of bed and start. I’ve never skipped a remote session but in-person can be a chore. You don’t need fancy home equipment, and nothing at all to start. Costs about $40/session so $500/month. The more weight you lose the more energy you have and the easier it is to keep up with the exercise. I actually do some Apple Fitness classes now even for fun.

As for business opportunity, this is a market a ton of TRT / life extension clinics and concierge doctors are already serving.

Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#58

Post by CrHn3 »

Here are some things I have been trying. To me, it seems there is a loss of microbial function for many people that is contributing to metabolic disfunction. Prebiotics and synbiotics can be used in combination with diet to combat dysbiotic microbiomes in obese individuals [1]. Obesogenic memory is mediated by dysbiotic strains of bacteria, and oral bacteria play a role (you can get oral probiotics and they're more likely to be persistent after a cleaning when the biofilm has been removed).

Evivo with 2'FL from Layer Origins, a synbiotic prebiotic for this strain. My code is EVIVO-1075 if you want 15% off. It's been successfully engrafted in adults [2] and improving acetate, lactate, and butyrate (byproducts of breaking down the HMO) seems to be correlated with better diabetes outcomes, less inflammation and potential appetite modulation [3]. Bifidobacteria have potential to be protective against T2D [4].

Akkermansia muciniphila with a Layer Origins Super Reds [5, 6]. It's a chicken and egg problem, but reduced Akkermansia muciniphila is associated with obesity and supplementation seems to improve metabolic disorder, but research is limited.

Omega-3 and more poly and mono unsaturated fats [7]. Omega-3 reduced all-cause and cause-specific mortality in diabetes patients [8]. I was vegetarian for a long time and avoided saturated fat, then started eating more when I got into Weston A. Price and started keto and continued to eat moderate fat when not doing a low carb diet. Long term, I've had issues with satiety and discipline even with keto, while a diet with grains helps me feel fuller longer. My sibling did 23 and me and found out they have variation on alleles associated with higher weight with increased saturated fat consumption, which has made me reconsider what kinds of fats I consume [9].

Inositol and COQ10 [10]. Peter Langsjoen, who pioneered the research on ubiquinol, has said he has the healthiest cardiology patients and attributed it to ubiquinol. You need a dose high enough to maintain a certain blood serum level and ubiquinol is water soluble where cheaper ubiquinone is less readily absorbed.

Gluten can be inflammatory for people, and I found this talk helpful for understanding more about leaky gut and dysfunction: https://www.youtube.com/watch?v=evQAzGaW1JU. Emulsifiers have been shown to alter microbiota composition, so less processed foods is probably wise [11]. Dishwasher pods and rinse aids contain alcohol ethoxylates that can disrupt the microbiome but you can find ones that clean decently without them.

1. https://bnrc.springeropen.com/articles/10.1186/s42269-023-01...

2. https://www.cell.com/cell-host-microbe/pdfExtended/S1931-312...

3. https://www.science.org/doi/10.1126/science.aao5774

4. https://www.thelancet.com/journals/ebiom/article/PIIS2352-39...

5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310354/

6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856456/

7. https://www.mdpi.com/2075-1729/13/6/1322

8. https://link.springer.com/article/10.1007/s00592-022-02003-w

9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214897/

10. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5...

11. https://www.sciencedaily.com/releases/2015/02/150225132105.h...

Re: Ask HN: If you could spend $100k to get healthy and fit, how would you do it?

#60

Post by CrHn3 »

InTheFutureRob wrote: post #53

Carnivore is FOOLISH. There is no Scientific evidence whatsover that it benefits anything aside from short term weight loss, at the detriment of your health. I would get my whole genome sequenced and get a genetic counselor. Get a personal trainer and an expert on human performance (Get tested from athletic labs you can measure your VO2 max, RMR, Body composition and create a workout routine optimizing for longevity…

Some think that statins stimulate atherosclerosis and heart failure

https://cardiacos.net/wp-content/uploads/2019/04/2015-Statin...

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