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Association between cannabis use and subjective cognitive decline

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Re: Association between cannabis use and subjective cognitive decline

#51
post #5

> The reason for cannabis use, but not frequency and method, is associated with SCD. Further research is needed to investigate the mechanisms that may contribute to the observed associations between non-medical cannabis use and decreased odds of SCD.

What is SCD?

Subjective cannabis delinquency

Re: Association between cannabis use and subjective cognitive decline

#52

Subjective cognitive decline is a 'subjective' because it is perceived by the individual themselves. This means one of: 1) Weed dramatically reduces cognitive impairment. 2) Weed dramatically reduces an individual's ability to accurately asses their cognitive ability. 3) People who use weed are, for some other reason, dramatically less likely to suffer from cognitive impairment, or dramatically less able to accuratel…

From my personal experience, having several friends that have been smoking since high school up to now (mid 30s), it's definitely 2).

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Re: Association between cannabis use and subjective cognitive decline

#54

Subjective cognitive decline is a 'subjective' because it is perceived by the individual themselves. This means one of: 1) Weed dramatically reduces cognitive impairment. 2) Weed dramatically reduces an individual's ability to accurately asses their cognitive ability. 3) People who use weed are, for some other reason, dramatically less likely to suffer from cognitive impairment, or dramatically less able to accuratel…

From my personal experience, having several friends that have been smoking since high school up to now (mid 30s), it's definitely 2).

It's pretty well established that using cannabis while the brain is still developing has a negative impact on brain development. Additionally, from what I've observed among a few dozen people I've known over the years, people who start smoking in high school and continue without any substantial breaks through to adulthood tend to have a less healthy relationship with cannabis. They have a stronger tendency to fall into the pattern of using all day every day, and tend use much larger amounts than people who started using as adults or have taken substantial breaks (year +) from cannabis consumption as adults.

Re: Association between cannabis use and subjective cognitive decline

#55
post #36

Subjective cognitive decline is a 'subjective' because it is perceived by the individual themselves. This means one of: 1) Weed dramatically reduces cognitive impairment. 2) Weed dramatically reduces an individual's ability to accurately asses their cognitive ability. 3) People who use weed are, for some other reason, dramatically less likely to suffer from cognitive impairment, or dramatically less able to accuratel…

I have a sort of alternative explanation to your four. One thing I've noticed with pot smokers is that many seem to be almost in love with the drug. I have had people try to explain to me the manifold benefits of hemp fibers or CBD or how cannabis kills cancers. I think this could quite plausibly extend to survey answers, where saying they suffer from cognitive decline would be a kind of admission of defeat and go ag…

It's really a culture. People smoke cannabis to feel part of a clan or a cult, and then get hooked to the psychoactive effects.

It's always a game of social influence at the beginning, and sometimes later on.

Eventually, you may be pushed to smoke if you want to feel part of a social group and culture, and then, once inside, you have to follow the codes of it.

A large part of the cannabis cult(ure) is to preach the substance to everybody around you, to get it depenalized, legalized, and want everybody to have good views on it so they can take it more in public, and be socially more accepted, not considered like a junkie.

The end-game of it, is to do everything to get more of it, consciously or not.

Then, from that perspective, now you have someone that asks you: "is cannabis good for you ?" (just in other words).

Your goal to consume cheaper and higher quality of the substance, without legal risks, and to have approval of your friends, then what do you say ?

Of course "yes it's great".

There is also a survivorship bias in the study: once you feel that your cognitive abilities decline, you typically stop smoking cannabis.

The extreme case: people with dementia are automatically excluded because they cannot even smoke or purchase the product.

Re: Association between cannabis use and subjective cognitive decline

#56
post #21

That's odd considering cannabis use was shown to decrease REM sleep and thus memory processing and consolidation.

CBD on the other hand in "mid range" doses decreases REM sleep latency and (any dose?) also decreases REM sleep suppression related to anxiety. This is something that I imagine needs more study, as there is a huge variability in THC to CBD ratios in legally available cannabis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116407

Although most recreational cannabis is high THC : low CBD, there is ever-growing demand for more balanced strains. There's no telling what the average looks like in black and grey markets (although high THC is certainly the default assumption given its intoxicating effects). Before we make blanket statements about the impact of cannabis on sleep, we should probably seek to answer questions like, what is the overall impact on REM sleep with cannabis that has a 4:1 ratio of THC to CBD or lower?

Re: Association between cannabis use and subjective cognitive decline

#57

Subjective cognitive decline is a 'subjective' because it is perceived by the individual themselves. This means one of: 1) Weed dramatically reduces cognitive impairment. 2) Weed dramatically reduces an individual's ability to accurately asses their cognitive ability. 3) People who use weed are, for some other reason, dramatically less likely to suffer from cognitive impairment, or dramatically less able to accuratel…

Strong likelihood of 4.

“The reason for cannabis use, but not frequency and method, is associated with SCD.”

The finding is clearly an artifact of the methodology. BRFSS is probably not the right way to study this.

Re: Association between cannabis use and subjective cognitive decline

#58

Earlier quoted context omitted.

There should be a whole library of such studies, perhaps even with more than one successful replication. All signal, no noise. Entire disciplines would be absent from it

Imagine if academic success were measured by having studies in such a library. Not just the original, but also the replications! Somehow we'd also need to incentivize publications of non-successful replications just as much though.

I wonder what an action plan to make this happen would look like.

It would appear that many researchers are aware the system is suboptimal but are resigned to it, or even benefit from it.

Maybe we should pitch a tech billionaire to fund a journal like this.

Re: Association between cannabis use and subjective cognitive decline

#59

Subjective cognitive decline is a 'subjective' because it is perceived by the individual themselves. This means one of: 1) Weed dramatically reduces cognitive impairment. 2) Weed dramatically reduces an individual's ability to accurately asses their cognitive ability. 3) People who use weed are, for some other reason, dramatically less likely to suffer from cognitive impairment, or dramatically less able to accuratel…

Marijuana tends to affect people in one of two ways: they either get subdued or they get infatuated. Many people appear to get calmed and relaxed, they could just go to sleep, with pot affects them. Those that marijuana infatuate tend towards creative, intellectual, and creative intellectual pursuits. I am one such infatuated pot smoker, which I keep pretty much secret, because due to my pot smoking infatuations I've…

This sounds like classic indica verse sativa descriptions; the former being "couch lock" while the latter is "mental input seeking."

As a daily smoker (for over two decades), I definitely seek BOTH states of mind.

Regardless, glad to see you've remained fascinated with your career.

Re: Association between cannabis use and subjective cognitive decline

#60

Earlier quoted context omitted.

Marijuana tends to affect people in one of two ways: they either get subdued or they get infatuated. Many people appear to get calmed and relaxed, they could just go to sleep, with pot affects them. Those that marijuana infatuate tend towards creative, intellectual, and creative intellectual pursuits. I am one such infatuated pot smoker, which I keep pretty much secret, because due to my pot smoking infatuations I've…

This sounds like classic indica verse sativa descriptions; the former being "couch lock" while the latter is "mental input seeking." As a daily smoker (for over two decades), I definitely seek BOTH states of mind. Regardless, glad to see you've remained fascinated with your career.

Kinda, with couch lock I can work (nothing too analytical tho), whereas sativa is so intense and panic inducing that I can’t even focus on a movie.

Afaik CBD counteracts the mind infatuation but leaves the body high on.

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