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"AI will cure cancer" misunderstands both AI and medicine

rachel.fast.ai

11–20 of 207 posts

Re: "AI will cure cancer" misunderstands both AI and medicine

#11

Saying you'll cure cancer with AI without specifying the type of cancer is like declaring you'll solve crime with Batman. Way too broad to be useful, but makes a good headline.

I'm curious about the presumed language.

When we say "She has cancer" we mean "a cancer". (Hopefully she doesn't have all of them!). Why couldn't the sentence "AI will cure cancer" mean "a cancer" as well?

Re: "AI will cure cancer" misunderstands both AI and medicine

#13

Sad to hear of Ilene Ruhoy’s experience here. She is a wonderful clinician who has enormously helped other patients with complex diagnostic paths and with diagnoses that are severely neglected.

I also share the author’s concerns.

I keep coming back to the fact that if you asked even GPT 3 how to solve climate change, it would give you a perfectly good answer. We have this idea that AI will “solve climate change” at some point in the future. What we really mean is “give us a different answer to climate change that has zero cost”.

Climate change is not currently being solved because of politics and existing systems, not because of a lack of intelligence.

There are so many similar situations in medicine. Intelligence is not enough- you also need a system capable of acting with that intelligence.

AI could be transformational, but not without systemic change to support it.

Re: "AI will cure cancer" misunderstands both AI and medicine

#14
post #5

Saying "AI will cure cancer" is like saying "science will cure cancer" or "doctors will cure cancer". In general, all three statements are true about technological progress. > Second, AI is used to disproportionately benefit the privileged while worsening inequality. That's bullshit. Computers and other gadgets always start out as toys of the rich, but they quickly trickle down to everyone else. Compare the multi-tho…

> Computers and other gadgets always start out as toys of the rich

But is this a function of moore's law? I have to say that OpenAI's training costs seems to be growing exponentially, not declining exponentially.

Re: "AI will cure cancer" misunderstands both AI and medicine

#15
post #12

"AI will..." is either the som of human hopes and dreams, or the sum of human fears. I wonder if industrialization was anything like this (though I don't think ML will end up being comparable to the industrial revolution).

>> is either the som of human hopes and dreams, or the sum of human fears

Or Sam Altman pumping his fund.

Re: "AI will cure cancer" misunderstands both AI and medicine

#16
post #12

"AI will..." is either the som of human hopes and dreams, or the sum of human fears. I wonder if industrialization was anything like this (though I don't think ML will end up being comparable to the industrial revolution).

>> is either the som of human hopes and dreams, or the sum of human fears Or Sam Altman pumping his fund.

Aka the sam of human fears

Re: "AI will cure cancer" misunderstands both AI and medicine

#18

Saying you'll cure cancer with AI without specifying the type of cancer is like declaring you'll solve crime with Batman. Way too broad to be useful, but makes a good headline.

I'm curious about the presumed language. When we say "She has cancer" we mean "a cancer". (Hopefully she doesn't have all of them!). Why couldn't the sentence "AI will cure cancer" mean "a cancer" as well?

"She has cancer" is a specific event, so we logically deduce that it is "a type of cancer".

When you say "AI will cure cancer" that is not a singular event, so you assume cancer in the plural. You would have to say "AI will cure some forms of cancer" if you didn't mean the plural here.

Re: "AI will cure cancer" misunderstands both AI and medicine

#19

Saying you'll cure cancer with AI without specifying the type of cancer is like declaring you'll solve crime with Batman. Way too broad to be useful, but makes a good headline.

I kind of feel like that's exactly why AI is helpful here:

- Grab a cancer (or virus, bacteria, etc.)

- Sequence it

- AI will develop a custom therapy for that cancer

In broad strokes, it's not hard to develop a therapy for any specific cancer or other disease in a specific individual. There are several broad strategies:

- A targeted, custom phage to kill a bacteria (or extrapolate to killing a type of cells)

- A custom vaccine to make your body make antibodies specific to a disease

- And so on....

This is a ≈2 year research effort to do in each case, and perhaps a ≈10 year validation effort, not to mention regulatory. By that point, the patient is dead, or AIDS has mutated a few dozen times, and regardless, you need a massive research team to do so. And to do so, you've spent many million dollars on a research team that whole time.

"AI will cure [X]" consists of AI doing the same thing instantly. I go to a doctor. My chronic disease is sequenced. My specific immune system is encouraged to attack that specific disease. I'm cured.

(And yes, we each have a very different immune system; see MHC for an example of how and why)

Re: "AI will cure cancer" misunderstands both AI and medicine

#20
In my not so humble opinion, AI will help medicine and will accelerate the design of new cancer therapies. Curing all possible forms of cancer almost seems like a red herring, given how fragile the human cells are, and how these cells generally become more fragile with respect to becoming cancerous as we age. However, better drug therapies will eventually make cancer a more manageable condition for a large fraction of the population and hopefully for everyone in the long term. I am sure the realities of the current health care system will be dramatically different than those of healthcare in 100 years from now. I agree with Rachel that patient led medical research is a very important area that is greatly aided by AI and will have an impact in medicine.
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