One of my favorite questions is: "What's the best bug you've ever found?" Usually I get a "Huh?" The really stellar folks will tell you about the bug that took two weeks to find and boiled down to a single missing comma in a vendor's library routine. Or /something/. But "Huh" is a bad sign. "Huh?" is not a fail, but it usually correlates with people who can't write a function to find the length of a string, and I see…
One of the problems I always have with questions like that is this: I don't keep mental lists of events or other things ordered by potential "interestingness" to myself or other people. I just don't think that way for some reason.
I might fumble to come up with an answer to that question, and then an hour after the interview is over, I'll remember a really good story the interviewer would have liked, but in the meantime I've looked like an inexperienced, bumbling fool.
Not that it really matters, of course--eventually I'll get through an interview without hitting a question that doesn't work for me, get hired, and then actually get to do some good work for somebody. Getting through that process feels fairly random to me.