You're likely describing citizen science and engineering, which cannot really be considered for publication in Nature.
The work here represents many thousands if not millions of hours of accumulated scientific skill in building experiments that are likely to produce useful conclusions, rather than falsely rejecting the null hypothesis.
I've worked in citizen science and I have even done some exciting stuff in my garage, which attracted the world's leading researcher in my area of interest. The first thing I'd need to do with my tech is to bring it to his lab and reproduce it on science-grade equipment. then we would need to come up with good hypotheses we could test, and spend an enormous amount of time designing protocols, and debugging lab details. All of that comes before even thinking about writing a manuscript that would be accepted in nature, which is one of the most prestigious journals with enormous readership.
I don't want to discourage young folks who want to get into science, but the reality is that the vast majority of real science is dull work, such as requesting money, writing presentations to convince people you're right, and debugging experiments. I'm not defending this as the way it should be, but observing the reality of the situation. I have actually met a very small number of people who managed to turn citizen science into Big Science and get published, but they are a much smaller group than the folks who do bad citizen science in their garages and get attention on sites like Hackaday.