Earlier quoted context omitted.
Reminds of this PG quote: > If you imagine someone with 100 percent determination and 100 percent intelligence, you can discard a lot of intelligence before they stop succeeding. But if you start discarding determination, you very quickly get an ineffectual and perpetual grad student. Not the same source, but similar message and very much worth the watch: https://www.youtube.com/watch?v=t8TwkfxEdJ0
Nothing in this world can take the place of persistence. Talent will not: nothing is more common than unsuccessful men with talent. Genius will not; unrewarded genius is almost a proverb. Education will not: the world is full of educated derelicts. Persistence and determination alone are omnipotent. -- Ronald Reagan
Determination and persistence is only effective with a goal or vision that comes from the heart. Then the quote is true. But both words are hijacked by everyone from managers and linked-in gurus to inspire another day of artificial purpose. Meaning cannot be manufactured.