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Long Covid is associated with cognitive slowing

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Re: Long Covid is associated with cognitive slowing

#2
These numbers don't look so great long term. Especially the no PCC group. The good news is that recent research suggests we can start aggressively targeting virus in trials:

https://www.nature.com/articles/s41590-023-01724-6

https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v...

There are a lot of exciting trials going on for many different antivirals, monoclonal antibodies, immunomodulators/immunotherapy, and even novel molecules to help clear out viral persistence.

I am starting to collect these budding treatments & patient stories as they come on a website here:

https://www.lctreatments.com/

Re: Long Covid is associated with cognitive slowing

#5
Not sure if others have experienced this, but you tend to forget nouns (object names, names of people, places, etc) after getting hit with COVID. I googled about this and something called "anomic aphasia" came up.

I often caught myself saying "that thing" many times because I couldn't recall the names of even basic objects or street names, etc after getting hit with Omicron.

Just curious if others have experienced this as well.

Re: Long Covid is associated with cognitive slowing

#7

These numbers don't look so great long term. Especially the no PCC group. The good news is that recent research suggests we can start aggressively targeting virus in trials: https://www.nature.com/articles/s41590-023-01724-6 https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v... There are a lot of exciting trials going on for many different antivirals, monoclonal antibodies, immunomodulators/immunotherapy, a…

There was some recent study where most patients who received monoclonal antibodies regressed rapidly so I am not sure that's a good pathway. The hypothesis is that the covid antibodies are quite nasty so the body creates anti-antibodies that in turn resemble the original virus wrt certain effects and one ends up in a cycle of doom that first needs to be broken before one starts getting better.

Re: Long Covid is associated with cognitive slowing

#8
post #3

[flagged]

> just that there is no real evidence of this being a real disease

What does this even mean? How do you define a 'real' disease?

Sounds like a god of the gaps fallacy to me. Just because we don't understand and can't treat it yet doesn't mean it's not a real disease. At the very least it looks like a cluster of various kinds of diseases.

Re: Long Covid is associated with cognitive slowing

#9
post #3

[flagged]

Cognitive slowing squares with the depression hypothesis.

More like with neuroinflammation and brain hypoperfusion? Both present and measured in long covid sufferers. M1 polarized microglia, damaged endothelium, dysfunctional mitochondria...

Re: Long Covid is associated with cognitive slowing

#10
post #3

[flagged]

There is no evidence that your claims are worth anything.

There are tons of known mechanisms, biomarkers, documented physiological alterations and on and on and on.

Do take note that “there is no evidence for x” is an absolutely gargantuan claim. If you intend to carve swathes of epistemological foundations into the void you better have something a little sharper and a little more substantial.

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