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When America first dropped acid

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Re: When America first dropped acid

#51

Post by pennaMan »

anjel wrote: post #50
ericmcer wrote: post #23

Earlier quoted context omitted.

The effects of low doses of mushrooms/MDMA make me wonder if we have been going about it all wrong. You can easily take 20% of the normal amount and have a pleasant and noticeable effect but still be highly functional. It is like our "normal" dose for those drugs is the equivalent of 6+ drinks, and the idea of only having a beer or two is painted as a waste.

Micro dosing psylocibe/psylocin on a regular basis puts your heart valves at some risk of permanent damage in ways occasional high dose use does not.

You got a reference to back that up?

Re: When America first dropped acid

#52

Post by quchen »

thow16161 wrote: post #32
thinkingtoilet wrote: post #10

I'm curious to see how many people have access to mushrooms these days. For my 20s and 30s it seemed impossible to get, now all of a sudden I can get them no problem. I have a friend who is not into drugs at all but grows them, weighs them, and has a pill making machine to make pills so he can accurately micro-dose to address severe depression. I have other friends who love drugs and can get the literally anytime the…

Yes, they've gotten easier. There are mushroom based gummies available in local smokeshops due to some loophole in the that this particular strain of shrooms is not explicitly illegal. My gf just got into shrooms. She started getting them from her weed dealer. His shrooms were overpriced, and hit or miss quality. Then we ran into a girl with a shroom hat at a festival, and it turns out she's a great source. Selling s…

> hit or miss quality

Psiloc(yb)in content varies a lot among fruiting bodies of the same batch, genome, flush, hell even within the same cluster (example papers [1][2]). So even for known/good sources I would suggest mixing at least a couple of fruiting bodies to have something known and repeatable. Since powder degenerates faster, honey is a good water/air/light free preservative.

[1]: https://pubmed.ncbi.nlm.nih.gov/17401967/ [2]: https://www.sciencedirect.com/science/article/abs/pii/037887...

Re: When America first dropped acid

#53

Post by photochemsyn »

Depending on how you define America, use of psychedelics goes back a bit further than the 20th century, or the arrival of Europeans. For example, here's a nice overview of the history of mescaline, the active ingredient in peyote cactus:

https://medicalhealthhumanities.com/2019/09/17/from-the-dese...

Re: When America first dropped acid

#54

Post by babyshake »

pennaMan wrote: post #51
anjel wrote: post #50

Earlier quoted context omitted.

Micro dosing psylocibe/psylocin on a regular basis puts your heart valves at some risk of permanent damage in ways occasional high dose use does not.

You got a reference to back that up?

Yes, this is the first I've heard of this but I would be interested in learning about it.

Re: When America first dropped acid

#55

Post by latchkey »

I recently ran out of gummies. Thanks to things being legal now, I just went to the handy Eaze website to do an order.

$70 of goods + $30 in taxes and fees.

Is this what libertarians mean by "taxation is theft?"

Re: When America first dropped acid

#57

Post by feedforward »

ldjkfkdsjnv wrote: post #13

Recently read a description of 1960's ideology. The claim being that its all propaganda, and what we know as 60s ideology (peace love etc) actually never really happened for a real duration of time. What did happen was that those that prescribed to that line of thinking either moved to communes, or they dropped so much acid they were societally irrelevant. There werent many people actually out and about that were pus…

There's almost universal opinion on the mainstream, left and right that a cultural shift happened in the US between Eisenhower leaving office and Woodstock. It's not some narrative invented and pushed out.

The media does manufacture narratives. Youth in New York and San Francisco had a subculture in the 1950s which was framed as beatnik, and soon sitcoms were mocking beatnik. Small basement performance places would have patrons not clap to avoid noise complaints, so patrons would snap their fingers as applause. This was then presented as something unusual and pretentious, minus its original context. The same thing with San Francisco hippies - they arose organically, the mainstream culture took notice of them and presented them a certain way, and the cycle goes on.

Every social movement that arises is met with an attempt to coopt and to commodity by the corporate media and corporate America, this has happened for a long time.

Re: When America first dropped acid

#59

Post by financltravsty »

babyshake wrote: post #54
pennaMan wrote: post #51

Earlier quoted context omitted.

You got a reference to back that up?

Yes, this is the first I've heard of this but I would be interested in learning about it.

Psilocybin is a partial 5-HT2B receptor agonist. 5-HT2B receptor agonism causes deposits of collagen in heart valves (which will lead to valve disease). This is true for LSD, MDMA, and psilocybin.

A note is that psilocybin is only a partial agonist, and the dosages taken for micro-dosing may not be comparable to something like fenfluramine (a drug which does cause heart valve dysfunction for certain). There was a drug nerds thread lying around on Reddit where the theoretical receptor activations were compared. IIRC, psilocybin is not a major risk, as long as you're not tripping every day for months on end.

Re: When America first dropped acid

#60

Post by midiguy »

ericmcer wrote: post #23
lemonberry wrote: post #6

I take psychedelics a few times a year. I'm good with LSD once a year and I'm ok skipping it. I enjoy low (not micro) doses of mushrooms a few times each summer. Both have been very good for my sobriety. They aren't for everyone though. Great to see this becoming mainstream. Sad to see the number of charlatans and the industry has popped up around it. I hope that we're able to safely get these substances to those tha…

The effects of low doses of mushrooms/MDMA make me wonder if we have been going about it all wrong. You can easily take 20% of the normal amount and have a pleasant and noticeable effect but still be highly functional. It is like our "normal" dose for those drugs is the equivalent of 6+ drinks, and the idea of only having a beer or two is painted as a waste.

Microdoses have no real effect on me at best, and put me totally on edge at worst. But I love a mild 1-2g trip. I personally think the optimal dose is a mild tripping dose (perhaps mid ~3.5g if you are experienced and are looking for that kind of experience).

But at the end of the day, everyone reacts different. I don't know if there is a point to characterizing what should be 'normal' dosage. They are basically completely different drugs with different uses at different doses.

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