I receive a lot of physical mail from HelloFresh and there's no clear way to opt-out. I've never (willingly or knowingly) signed up to their service or any marketing bits.
I've been getting tons of physical mail I didn't ask for for years. We need a spam filter for the USPS. I only check my mailbox when I know something I want is coming, or if I need some grocery ads for kindling, because it's all garbage. It drives me insane how wasteful it is, chopping down trees just to make mailers that noone wants.
Most often I encounter people who actually get angry at me for not having a mailbox, call me selfish, call me the unibomber, tell me it is illegal. I still cannot figure out why people get emotionally charged about it.
A short while after I did it, the USPS reported to HUD that my address was vacant, and HUD reported that to the bank that holds my mortgage. This of course freaked them out until I explained to them what was going on.
I was also unable to take advantage of the free Covid test kits that the Federal government said were available to "every family in America". Turns out it was really every family in America with a residential mailbox. Ok, that was my choice, but there *are* still rural communities that rely on general delivery at the post office rather than individual mailboxes.
I do occasionally hit companies who's web app will tell me my address isn't good because it is a business address instead of a residential address. They are few enough though that I can just not do business with them and it hasn't impacted me much.